Concise enantioselective synthesis of wine lactone via intramolecular Diels-Alder reaction.

An enantioselective synthesis of (3S,3aS,7aR)-wine lactone, a major aroma component of white wine and citrus juices, was achieved starting from (S)-2-methyl-3-butenoic acid. An intramolecular Diels-Alder reaction was employed as a key step. © The Author(s) 2021. Published by Oxford University Press on behalf of Japan Society for Bioscience, Biotechnology, and Agrochemistry.

Citation

Yasutaka Ohkubo, Yui Masuda, Yusuke Ogura, Hirosato Takikawa, Hidenori Watanabe. Concise enantioselective synthesis of wine lactone via intramolecular Diels-Alder reaction. Bioscience, biotechnology, and biochemistry. 2021 May 25;85(6):1390-1394

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PMID: 33720279

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