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A size checkpoint active during cell proliferation ensures that cells reach a certain target size before transitioning into S phase. In this issue of Developmental Cell, Tan et al. identify a distinct function of cyclin-dependent kinase 4 (CDK4) in determining the target cell size for cell cycle progression. Copyright © 2021 Elsevier Inc. All rights reserved.
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Yiqin Ma, Bruce A Edgar. CDK4: Linking cell size to cell cycle control. Developmental cell. 2021 Jun 21;56(12):1695-1696
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PMID: 34157303
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