Use of Recombinant Factor VIIa for Bleeding Control in Treatment of Acute Extremity Compartment Syndrome Secondary to Primary Myelofibrosis: A Case Report.

Mehmet Demirel, Alper Şükrü Kendirci, Emre Özmen, Gökhan Polat

JBJS case connector 2021 Jul 28

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A 40-year-old man was admitted to our emergency department with a painful and swollen calf. There was no history of significant trauma, and the physical examination revealed a pulseless, swollen left lower leg. Clinical history revealed a diagnosis of primary myelofibrosis, and magnetic resonance imaging showed a rupture of the gastrocnemius medial head. The diagnosis of spontaneous acute extremity compartment syndrome (AECS) secondary to myelofibrosis was established. An open fasciotomy procedure was performed, and recombinant factor VIIa treatment was applied to control bleeding. Postoperatively, fasciotomy wounds were closed with skin grafts. AECS may develop in patients with bleeding disorders, and recombinant factor VII may help control bleeding. Copyright © 2021 by The Journal of Bone and Joint Surgery, Incorporated.

Citation

Mehmet Demirel, Alper Şükrü Kendirci, Emre Özmen, Gökhan Polat. Use of Recombinant Factor VIIa for Bleeding Control in Treatment of Acute Extremity Compartment Syndrome Secondary to Primary Myelofibrosis: A Case Report. JBJS case connector. 2021 Jul 28;11(3)