Gli1+ Mesenchymal Stem Cells in Bone and Teeth.

Yange Wu, Xueman Zhou, Wenxiu Yuan, Jiaqi Liu, Wenke Yang, Yufan Zhu, Chengxinyue Ye, Xin Xiong, Qinlanhui Zhang, Jin Liu, Jun Wang

Current stem cell research & therapy 2022

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Mesenchymal stem cells (MSCs) are remarkable and noteworthy. Identification of markers for MSCs enables the study of their niche in vivo. It has been identified that glioma-associated oncogene 1 positive (Gli1+) cells are mesenchymal stem cells supporting homeostasis and injury repair, especially in the skeletal system and teeth. This review outlines the role of Gli1+ cells as MSC subpopulation in both bones and teeth, suggesting the prospects of Gli1 an + cells in stem cell- based tissue engineering. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Citation

Yange Wu, Xueman Zhou, Wenxiu Yuan, Jiaqi Liu, Wenke Yang, Yufan Zhu, Chengxinyue Ye, Xin Xiong, Qinlanhui Zhang, Jin Liu, Jun Wang. Gli1+ Mesenchymal Stem Cells in Bone and Teeth. Current stem cell research & therapy. 2022;17(6):494-502