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gli1 protein
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Curated Studies
Most Correlated Studies
Medulloblastomas resulting from Atoh1- or Gli1-overexpressing granule neuron progenitor cells (GNPs)
T-cell lymphoma CUTLL1 cells with CRISPR/Cas9-induced GLI1 knockout
Neuroblastoma SH-SY5Y cells treated with GM6 peptide
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Literature
Most Relevant Literature
MRCKα/β positively regulates Gli protein activity.
GLI transcriptional repression is inert prior to Hedgehog pathway activation.
Garcinone C Suppresses Tumorsphere Formation and Invasiveness by Hedgehog/Gli1 Signaling in Colorect…
Fine-Tuning of GLI Activity through Arginine Methylation: Its Mechanisms and Function.
Targeting GLI proteins in human cancer by small molecules (WO2014116651 A1): a patent evaluation.
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Most Relevant Clinical Trials
A Phase 1 Study of ZSP1602 in Participants With Advanced Solid Tumors
Treatment Duration Increment and Pharmacodynamic Study of CX-4945 in Patients With Basal Cell Carcin…
A Study of Vismodegib in Men With Metastatic CRPC With Accessible Metastatic Lesions for Tumor Biops…
Gemcitabine Hydrochloride With or Without Vismodegib in Treating Patients With Recurrent or Metastat…
GDC-0449 in Treating Patients With Locally Advanced or Metastatic Solid Tumors
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