Hua Zhu, Siping Hu, Yuntao Li, Yao Sun, Xiaoxing Xiong, Xinyao Hu, Junjing Chen, Sheng Qiu
Frontiers in immunology 2022Ischemic stroke after cerebral artery occlusion is one of the major causes of chronic disability worldwide. Interleukins (ILs) play a bidirectional role in ischemic stroke through information transmission, activation and regulation of immune cells, mediating the activation, multiplication and differentiation of T and B cells and in the inflammatory reaction. Crosstalk between different ILs in different immune cells also impact the outcome of ischemic stroke. This overview is aimed to roughly discuss the multiple roles of ILs after ischemic stroke. The roles of IL-1, IL-2, IL-4, IL-5, IL-6, IL-8, IL-9, IL-10, IL-12, IL-13, IL-15, IL-16, IL-17, IL-18, IL-19, IL-21, IL-22, IL-23, IL-32, IL-33, IL-34, IL-37, and IL-38 in ischemic stroke were discussed in this review. Copyright © 2022 Zhu, Hu, Li, Sun, Xiong, Hu, Chen and Qiu.
Hua Zhu, Siping Hu, Yuntao Li, Yao Sun, Xiaoxing Xiong, Xinyao Hu, Junjing Chen, Sheng Qiu. Interleukins and Ischemic Stroke. Frontiers in immunology. 2022;13:828447
PMID: 35173738
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