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Pyrrolo[2,1-a]isoquinolines occur frequently in a large number of bioactive natural products and pharmaceutically important molecules. The synthesis of pyrrolo[2,1-a]isoquinoline derivatives is an easy and useful way to produce artificial molecules with potential applications. A huge number of excellent methodologies for constructing pyrrolo[2,1-a]isoquinolines have been reported in the last decade. This review summarizes the recent advances in this research field covering from 2011 to 2021.


Hai-Lei Cui. Recent progress in the synthesis of pyrrolo[2,1-a]isoquinolines. Organic & biomolecular chemistry. 2022 Apr 06;20(14):2779-2801

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PMID: 35302153

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