Correlation Engine 2.0
Clear Search sequence regions

Sizes of these terms reflect their relevance to your search.

An efficient and enantioselective phosphonation protocol for construction of chiral α-aminophosphates and α-aminodiarylphosphine oxides has been developed based on chiral phosphoric acid-catalyzed dearomatization of isoquinolines. A series of chiral 1,2-dihydroisoquinolines with dimethoxy phosphoryl or diphenylphosphono substituents at the C1-position were constructed with good to excellent yields and enantioselectivities under mild reaction conditions.


Zhenhua Gao, Yongbiao Guo. Enantioselective phosphonation of isoquinolines via chiral phosphoric acid-catalyzed dearomatization. Chemical communications (Cambridge, England). 2022 Aug 18;58(67):9393-9396

Expand section icon Mesh Tags

Expand section icon Substances

PMID: 35912502

View Full Text