Probabilistic benefit-risk analysis of fish: Nutritional benefit versus methylmercury-contaminated risk.

Pinpin Lin, Pei-I Lee, Min-Pei Ling

Marine pollution bulletin 2023 Aug

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This paper carries out probabilistic approach to quantify the benefit-risk analysis for foods (BRAFO) of omega-3 polyunsaturated fatty acid and methylmercury (MeHg) for the people who eat the mercury-contaminated fish in Taiwan. We applied the hazard quotient (HQ) model to assess the risk of developmental neuropsychological impairment effect and the desirable dose index (DI) model to quantify the health benefits. Besides, we also applied the disability adjusted life years (DALY) model to assess the number of years lost by incidence of affected infants' intelligence quotient (IQ) and coronary heart disease (CHD) or Stroke for adult. The results of this study show that although the risk of cod and scad are higher, Taiwan residents do not need to reduce intake rate based on benefit considerations. Furthermore, according to the benefits of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), this study suggests that more intake of saury and salmon. Copyright © 2023 Elsevier Ltd. All rights reserved.

Citation

Pinpin Lin, Pei-I Lee, Min-Pei Ling. Probabilistic benefit-risk analysis of fish: Nutritional benefit versus methylmercury-contaminated risk. Marine pollution bulletin. 2023 Aug;193:115179