Profiling of phenolic compounds, antimicrobial, antioxidant, and hemolytic activity of mango seed kernel using different optimized extraction systems.

Kinza Saleem, Zafar Hayat, Zara Tariq, Tuba Riaz, Muhammad Azam

Journal of food science 2023 Dec

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Mango seed kernels (MSKs) have been reported to show antioxidant, antibacterial, and anti-inflammatory properties. This study explores the influence of different optimized extraction systems on the extraction of MSK. The effects on gallic acid (GA) content, total phenolic content (TPC), total flavonoid content (TFC), antioxidant, antimicrobial, and hemolytic activity of MSK extracts from different extraction systems (65.45% ethanol-ultrasound assisted extraction [UAE], 62% ethanol-incubator shaker, 19.4% ethanol-UAE, and 100% water-UAE) were assessed. Based on the results, a nonsignificant difference in phenolic (p = 0.222), flavonoids (p = 0.058), antioxidant (p = 0.165), and antimicrobial activity (p = 0.193) against Staphylococcus aureus whereas a significant difference (p < 0.0001) in hemolytic, GA content, and antimicrobial activity against Clostridium perfringens was observed. Among different extraction systems, aqueous extraction showed significantly lower hemolytic (1.09%) and higher GA content (4.72 mg/g) and comparable results in all other experiments; yield (32.40%), TPC (58.79 mg/g), TFC (2.16 mg/g), and antioxidant (73.19%). Hence, it has been concluded that aqueous extraction system could be considered a sustainable extraction system for practical applications. PRACTICAL APPLICATION: Aqueous extraction system could be a sustainable option for extraction of mango seed kernel for practical applications as it is readily available, cheap, nonflammable, and nontoxic. © 2023 International Development Research Centre (IDRC). Journal of Food Science published by Wiley Periodicals LLC on behalf of Institute of Food Technologists.

Citation

Kinza Saleem, Zafar Hayat, Zara Tariq, Tuba Riaz, Muhammad Azam. Profiling of phenolic compounds, antimicrobial, antioxidant, and hemolytic activity of mango seed kernel using different optimized extraction systems. Journal of food science. 2023 Dec;88(12):5002-5011