QuickView for A3R (gene)

Gene Symbol:

Adora3 Mus musculus

Full name:

adenosine A3 receptor

Synonyms:

A3AR, A3R, AA3R, ARA3, Gpcr2, adenosine receptor A3, G-protein coupled receptor 2

Genomic Location:

Chr 3: 105673825-105726954

Description:

This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibitio...

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This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. This gene shares its 3' terminal exon with a transcript variant from overlapping GeneID:69296, which encodes an immunoglobulin domain-containing protein.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  C. elegans ,  Macaca mulatta ,  Gallus gallus ,  Canis lupus familiaris ,  Pan troglodytes ,  Danio rerio ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATA1_03 ,  GATA_C ,  MAF_Q6 ,  PU1_Q6 ,  IRF1_Q6 ,  IRF_Q6 ,  GATA_Q6 ,  RGAGGAARY_PU1_Q6

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