QuickView for AdipoR2 (gene)

Gene Symbol:

ADIPOR2 Homo sapiens

Full name:

adiponectin receptor 2

Synonyms:

ACDCR2, PAQR2, adiponectin receptor protein 2, progestin and adipoQ receptor family member 2, progestin and adipoQ receptor family member II

Genomic Location:

Chr 12: 1670508-1768106

Description:

The adiponectin receptors, ADIPOR1 (MIM 607945) and ADIPOR2, serve as receptors for globular and full-length adiponectin (MIM 605441) and mediate increased AMPK (see MIM 602739) and PPAR-alpha (PPARA; MIM 170998) ligand activities, as well as fatty acid oxidation and glucose uptake by adiponectin (Yamauchi et al., 2003 [PubMed 12802337]).

The adiponectin receptors, ADIPOR1 (MIM 607945) and ADIPOR2, serve as receptors for globular and full-length adiponectin (MIM 605441) and mediate increased AMPK (see MIM 602739) and PPAR-alpha (PPARA; MIM 170998) ligand activities, as well as fatty acid oxidation and glucose uptake by adiponectin (Yamauchi et al., 2003 [PubMed 12802337]).

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TTTGCAC_MIR19A_MIR19B ,  GAGACTG_MIR452 ,  TFIII_Q6 ,  ATACCTC_MIR202 ,  TGCCTTA_MIR124A ,  TAXCREB_02 ,  CAGTATT_MIR200B_MIR200C_MIR429 ,  TGCACTT_MIR519C_MIR519B_MIR519A ,  CAGCCTC_MIR4855P ,  AAAGGAT_MIR501 ,  PAX4_01 ,  CCACACA_MIR147 ,  AAGCACA_MIR218

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for let-7 ,  Predicted Gene Targets for miR-19 ,  Predicted Gene Targets for miR-200b ,  Predicted Gene Targets for miR-218 ,  Predicted Gene Targets for miR-485-5p ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-124u ,  Predicted Gene Targets for miR-149 ,  Predicted Gene Targets for miR-375 ,  Predicted Gene Targets for miR-410 ,  Predicted Gene Targets for miR-496

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Cytogenetic Map:

12p13.33

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