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QuickView for BST1 (gene)


Gene Symbol:
BST1 Homo sapiens Homo sapiens
Full name:
bone marrow stromal cell antigen 1
Synonyms:
CD157, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2, ADP-ribosyl cyclase 2, NAD(+) nucleosidase, bone marrow stromal antigen 1, cADPr hydrolase 2, cyclic ADP-ribose hydrolase 2
Genomic Location:
Chr 4: 15313739-15342893
Description:
Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell a...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Cytogenetic Map:
chr 4
4p15.32





GO Molecular Function

NAD+ nucleosidase activity | hydrolase activity | hydrolase activity, hydrolyzing N-glycosyl compounds | lyase activity | catalytic activity | hydrolase activity, acting on glycosyl bonds | ADP-ribosyl cyclase activity | transferase activity | NAD+ nucleotidase, cyclic ADP-ribose generating | cyclic ADP-ribose hydrolase | NAD(P)+ nucleosidase activity | phosphorus-oxygen lyase activity | cyclase activity

GO Biological Process

regulation of leukocyte chemotaxis | exocytosis | regulation of B cell activation | neutrophil activation | regulation of localization | establishment of localization | regulation of immune system process | positive regulation of lymphocyte activation | regulation of organelle organization | cellular process | secretion | leukocyte degranulation | regulation of cell motility | localization | regulation of integrin-mediated signaling pathway | regulation of calcium-mediated signaling | nucleotide metabolic process | regulation of chemotaxis | regulation of cellular process | leukocyte activation | regulation of metabolic process | regulation of cellular extravasation | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | regulation of neutrophil chemotaxis | response to stimulus | neutrophil degranulation | regulation of peptidyl-tyrosine phosphorylation | positive regulation of immune system process | leukocyte activation involved in immune response | positive regulation of lymphocyte proliferation | regulation of cell proliferation | positive regulation of B cell proliferation | positive regulation of cell activation | secretion by cell | cellular nitrogen compound metabolic process | cofactor metabolic process | regulation of cell adhesion | positive regulation of mononuclear cell proliferation | regulation of superoxide metabolic process | nitrogen compound metabolic process | regulation of signal transduction | regulation of actin cytoskeleton organization | phosphorus metabolic process | leukocyte mediated immunity | regulation of granulocyte chemotaxis | regulation of phosphorylation | organophosphate metabolic process | regulation of lymphocyte activation | regulation of nitrogen compound metabolic process | regulation of cell migration | regulation of cell-substrate adhesion | small molecule metabolic process | vesicle-mediated transport | regulation of cellular component movement | nucleobase-containing small molecule metabolic process | regulation of cellular protein metabolic process | regulated exocytosis | regulation of leukocyte migration | phosphate-containing compound metabolic process | cell communication | regulation of cellular metabolic process | humoral immune response | cell activation involved in immune response | myeloid cell activation involved in immune response | regulation of protein metabolic process | neutrophil activation involved in immune response | positive regulation of cell proliferation | regulation of protein phosphorylation | regulation of locomotion | positive regulation of B cell activation | regulation of intracellular signal transduction | metabolic process | regulation of neutrophil migration | positive regulation of leukocyte activation | immune response | nucleobase-containing compound metabolic process | organic substance metabolic process | regulation of cell activation | regulation of phosphate metabolic process | cell activation | regulation of cell communication | signaling | nicotinamide nucleotide metabolic process | NAD metabolic process | regulation of reactive oxygen species metabolic process | regulation of B cell proliferation | neutrophil mediated immunity | heterocycle metabolic process | regulation of actin filament-based process | immune system process | cellular metabolic process | regulation of inflammatory response | regulation of cellular component organization | regulation of cytoskeleton organization | signal transduction | regulation of signaling | regulation of cell-matrix adhesion | regulation of phosphorus metabolic process

GO Cellular Component

secretory granule | integral component of membrane | extrinsic component of membrane | organelle membrane | cytoplasmic vesicle | cell | plasma membrane protein complex | intrinsic component of membrane | integrin complex | cytoplasm | intracellular organelle | receptor complex | secretory granule membrane | protein-containing complex | cell projection | secretory vesicle | endomembrane system | plasma membrane | vesicle | cell trailing edge | extracellular exosome | specific granule | anchored component of membrane | integral component of plasma membrane | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | vesicle membrane | extracellular space | cell periphery | protein complex involved in cell adhesion | intracellular vesicle | intracellular | specific granule membrane | membrane | uropod | cytoplasmic vesicle membrane | intrinsic component of plasma membrane