QuickView for CA5B;jsessionid=E1C542D2C9FA55D09933D66FBFFB87A2 (gene)

Gene Symbol:

CA5B Homo sapiens

Full name:

carbonic anhydrase 5B

Synonyms:

CA-VB, carbonic anhydrase 5B, mitochondrial, carbonate dehydratase VB, carbonic anhydrase VB, mitochondrial, carbonic dehydratase

Genomic Location:

Chr X: 15666333-15715669

Description:

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show...

View Full Description

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VB is localized in the mitochondria and shows the highest sequence similarity to the other mitochondrial CA, CA VA. It has a wider tissue distribution than CA VA, which is restricted to the liver. The differences in tissue distribution suggest that the two mitochondrial carbonic anhydrases evolved to assume different physiologic roles.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

PR_Q2 ,  PR_02 ,  GR_01

Cytogenetic Map:

Xp22.2

search → result