QuickView for CAV2;jsessionid=86F4B2D87AC2F696EF479EFC1A2E3E45 (gene)

Gene Symbol:

CAV2 Homo sapiens

Full name:

caveolin 2

Synonyms:

CAV, caveolin-2, caveolae protein, 20-kD, caveolin 2 isoform a and b

Genomic Location:

Chr 7: 115926680-115935831

Description:

The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. This gene and related family mem...

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The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. This gene and related family member (CAV1) are located next to each other on chromosome 7, and express colocalizing proteins that form a stable hetero-oligomeric complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Additional isoforms resulting from the use of alternate in-frame translation initiation codons have also been described, and shown to have preferential localization in the cell (PMID:11238462).

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

ATACTGT_MIR144 ,  TTGTTT_FOXO4_01 ,  TGGTGCT_MIR29A_MIR29B_MIR29C

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-29

Cytogenetic Map:

7q31.2

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