QuickView for CCDC115;jsessionid=200B78EB20321950392834B4BC960FB5 (gene)

Gene Symbol:

CCDC115 Homo sapiens

Full name:

coiled-coil domain containing 115

Synonyms:

CDG2O, ccp1, coiled-coil domain-containing protein 115

Genomic Location:

Chr 2: 130812286-130816392

Description:

The protein encoded by this gene has been observed to localize to the endoplasmic reticulum (ER)-Golgi intermediate compartment (ERGIC) and coat protein complex I (COPI) vesicles in some human cells. The encoded protein shares some homology with the yeast V-ATPase assembly factor Vma22p, and the orthologous protein in mouse promotes cell proliferat...

View Full Description

The protein encoded by this gene has been observed to localize to the endoplasmic reticulum (ER)-Golgi intermediate compartment (ERGIC) and coat protein complex I (COPI) vesicles in some human cells. The encoded protein shares some homology with the yeast V-ATPase assembly factor Vma22p, and the orthologous protein in mouse promotes cell proliferation and suppresses cell death. Defects in this gene are a cause of congenital disorder of glycosylation, type IIo in humans.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Pan troglodytes ,  Danio rerio ,  Bos taurus ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATTGGY_NFY_Q6_01 ,  NFY_Q6 ,  TAANNYSGCG_UNKNOWN

Cytogenetic Map:

2q21.1

search → result