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QuickView for CCL20 (gene)


Gene Symbol:
CCL20 Homo sapiens Homo sapiens
Full name:
C-C motif chemokine ligand 20
Synonyms:
CKb4, Exodus, LARC, MIP-3-alpha, MIP-3a, MIP3A, SCYA20, ST38, C-C motif chemokine 20, CC chemokine LARC, beta chemokine exodus-1, chemokine (C-C motif) ligand 20, liver and activation-regulated chemokine, macrophage inflammatory protein 3 alpha, small inducible cytokine subfamily A (Cys-Cys), member 20, small-inducible cytokine A20
Genomic Location:
Chr 2: 228386814-228390494
Description:
This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene displays chemotactic activity for lymphocytes and can repress prolif...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Gallus gallus Canis lupus familiaris Pan troglodytes Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 2
2q36.3


Transcripts Names
NM_004591
NM_001130046
Protein Names
P78556
Q99664
Q53S51



GO Molecular Function

chemokine activity | CCR chemokine receptor binding | signaling receptor binding | cytokine receptor binding | molecular function regulator | CCR6 chemokine receptor binding | chemokine receptor binding | protein binding | receptor regulator activity | G-protein coupled receptor binding | receptor ligand activity | cytokine activity

GO Biological Process

regulation of ERK1 and ERK2 cascade | positive regulation of macromolecule biosynthetic process | positive regulation of locomotion | response to cytokine | response to interleukin-1 | cell motility | response to lipopolysaccharide | intracellular signal transduction | regulation of localization | defense response to other organism | regulation of immune system process | cellular response to tumor necrosis factor | chemokine-mediated signaling pathway | defense response | positive regulation of phosphate metabolic process | positive regulation of cellular component movement | positive regulation of GTPase activity | positive regulation of cellular biosynthetic process | cellular process | regulation of cytokine biosynthetic process | regulation of cell motility | localization | chemokine activity | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | granulocyte chemotaxis | regulation of cellular process | cellular response to lipid | regulation of metabolic process | cellular response to molecule of bacterial origin | positive regulation of cellular protein metabolic process | thymocyte migration | cellular response to interferon-gamma | response to stimulus | neutrophil chemotaxis | positive regulation of immune system process | positive regulation of protein metabolic process | response to stress | positive regulation of T cell migration | lymphocyte chemotaxis | positive regulation of cytokine biosynthetic process | response to molecule of bacterial origin | G-protein coupled receptor signaling pathway | monocyte chemotaxis | cell-cell signaling | cell chemotaxis | molecular function regulator | leukocyte migration | locomotion | response to external biotic stimulus | regulation of signal transduction | cell migration | regulation of MAPK cascade | regulation of catalytic activity | regulation of phosphorylation | positive regulation of lymphocyte migration | wound healing | positive regulation of interleukin-1 alpha production | response to lipid | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of nitrogen compound metabolic process | regulation of cell migration | lymphocyte migration | cytokine-mediated signaling pathway | positive regulation of intracellular signal transduction | regulation of cellular component movement | positive regulation of hydrolase activity | second-messenger-mediated signaling | positive regulation of cell migration | cellular response to cytokine stimulus | regulation of cellular protein metabolic process | regulation of GTPase activity | regulation of leukocyte migration | response to bacterium | regulation of interleukin-1 production | cell communication | regulation of cellular metabolic process | positive regulation of interleukin-1 production | regulation of T cell migration | inflammatory response | regulation of protein metabolic process | positive regulation of signal transduction | leukocyte chemotaxis | defense response to bacterium | regulation of protein phosphorylation | regulation of locomotion | positive regulation of molecular function | calcium-mediated signaling | regulation of signaling receptor activity | receptor regulator activity | positive regulation of protein modification process | response to organic substance | response to wounding | regulation of intracellular signal transduction | cellular response to lipoteichoic acid | cell surface receptor signaling pathway | receptor ligand activity | immune response | cytokine activity | positive regulation of leukocyte migration | positive regulation of ERK1 and ERK2 cascade | regulation of phosphate metabolic process | response to interferon-gamma | positive regulation of cytokine production | positive regulation of MAPK cascade | positive regulation of interleukin-1 biosynthetic process | regulation of cell communication | signaling | positive regulation of phosphorylation | regulation of cytokine production | response to biotic stimulus | positive regulation of interleukin-1 alpha biosynthetic process | cellular response to interleukin-1 | calcium-mediated signaling using intracellular calcium source | innate immune response | T cell migration | positive regulation of metabolic process | immune system process | response to tumor necrosis factor | cellular response to organic substance | positive regulation of cell motility | neutrophil migration | chemotaxis | regulation of lymphocyte migration | response to other organism | positive regulation of signaling | signal transduction | mononuclear cell migration | regulation of signaling | positive regulation of nitric-oxide synthase biosynthetic process | cellular response to lipopolysaccharide | regulation of phosphorus metabolic process

GO Cellular Component

cell | extracellular region | extracellular space | intracellular