QuickView for CD73 (gene)

Gene Symbol:

NT5E Homo sapiens

Full name:

5'-nucleotidase ecto

Synonyms:

CALJA, CD73, E5NT, NT, NT5, NTE, eN, eNT, 5'-nucleotidase, 5'-NT, Purine 5-Prime-Nucleotidase, ecto-5'-nucleotidase

Genomic Location:

Chr 6: 86216528-86262215

Description:

The protein encoded by this gene is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects in this gene can lead to the calcification of joints and arteries. Two transcript variants encoding different ...

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The protein encoded by this gene is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects in this gene can lead to the calcification of joints and arteries. Two transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Bos taurus ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P ,  AAGTCCA_MIR422B_MIR422A

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-378*

Cytogenetic Map:

6q14.3

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