QuickView for CDC42BPB (gene)

Gene Symbol:

CDC42BPB Homo sapiens

Full name:

CDC42 binding protein kinase beta

Synonyms:

MRCKB, serine/threonine-protein kinase MRCK beta, CDC42 binding protein kinase beta (DMPK-like), CDC42BP-beta, DMPK-like beta, MRCK beta, myotonic dystrophy kinase-related CDC42-binding kinase beta, myotonic dystrophy protein kinase-like beta

Genomic Location:

Chr 14: 102468469-102593495

Description:

This gene encodes a member of the serine/threonine protein kinase family. The encoded protein contains a Cdc42/Rac-binding p21 binding domain resembling that of PAK kinase. The kinase domain of this protein is most closely related to that of myotonic dystrophy kinase-related ROK. Studies of the similar gene in rat suggested that this kinase may act...

View Full Description

This gene encodes a member of the serine/threonine protein kinase family. The encoded protein contains a Cdc42/Rac-binding p21 binding domain resembling that of PAK kinase. The kinase domain of this protein is most closely related to that of myotonic dystrophy kinase-related ROK. Studies of the similar gene in rat suggested that this kinase may act as a downstream effector of Cdc42 in cytoskeletal reorganization.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

ACACTCC_MIR122A ,  ZF5_01 ,  TTTGTAG_MIR520D ,  CAGTGTT_MIR141_MIR200A ,  CTTTGA_LEF1_Q2 ,  TCF4_Q5 ,  CTTTGTA_MIR524 ,  GTGCCAA_MIR96 ,  AAGWWRNYGGC_UNKNOWN ,  CCAWNWWNNNGGC_UNKNOWN ,  GGCNNMSMYNTTG_UNKNOWN ,  TGACAGNY_MEIS1_01 ,  ATGAAGG_MIR205

View More

View Less

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-122a ,  Predicted Gene Targets for miR-148 ,  Predicted Gene Targets for miR-141 ,  Predicted Gene Targets for miR-205 ,  Predicted Gene Targets for miR-27 ,  Predicted Gene Targets for miR-96

Cytogenetic Map:

14q32.32

search → result