QuickView for DGAT2 (gene)

Gene Symbol:

DGAT2 Homo sapiens

Full name:

diacylglycerol O-acyltransferase 2

Synonyms:

ARAT, GS1999FULL, HMFN1045, diacylglycerol O-acyltransferase 2, acyl-CoA retinol O-fatty-acyltransferase, diacylglycerol O-acyltransferase homolog 2, diacylglycerol O-acyltransferase-like protein 2, diglyceride acyltransferase 2

Genomic Location:

Chr 11: 75157456-75190225

Description:

This gene encodes one of two enzymes which catalyzes the final reaction in the synthesis of triglycerides in which diacylglycerol is covalently bound to long chain fatty acyl-CoAs. The encoded protein catalyzes this reaction at low concentrations of magnesium chloride while the other enzyme has high activity at high concentrations of magnesium chlo...

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This gene encodes one of two enzymes which catalyzes the final reaction in the synthesis of triglycerides in which diacylglycerol is covalently bound to long chain fatty acyl-CoAs. The encoded protein catalyzes this reaction at low concentrations of magnesium chloride while the other enzyme has high activity at high concentrations of magnesium chloride. Multiple transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

LEF1_Q2 ,  CAGGTG_E12_Q6 ,  GTGCCTT_MIR506

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-485-5p ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-374 ,  Predicted Gene Targets for miR-488 ,  Predicted Gene Targets for miR-543

Cytogenetic Map:

11q13.5

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