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QuickView for DNAJC6;jsessionid=6249F9C3C5331F9E46A49320767439F8 (gene)


Gene Symbol:
DNAJC6 Homo sapiens Homo sapiens
Full name:
DnaJ heat shock protein family (Hsp40) member C6
Synonyms:
DJC6, PARK19, putative tyrosine-protein phosphatase auxilin, DnaJ (Hsp40) homolog, subfamily B, member 6, DnaJ (Hsp40) homolog, subfamily C, member 6, auxilin
Genomic Location:
Chr 1: 65503018-65654140
Description:
DNAJC6 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus, a glycine/phenylalanine (G/F)-rich region, and a cysteine-rich domain containing 4 m...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Gallus gallus Pan troglodytes Canis lupus familiaris Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 1
1p31.3





GO Molecular Function

clathrin binding | SH3 domain binding | phosphatase activity | hydrolase activity | protein tyrosine phosphatase activity | catalytic activity | protein domain specific binding | phosphoprotein phosphatase activity | hydrolase activity, acting on ester bonds | protein binding | phosphoric ester hydrolase activity

GO Biological Process

protein dephosphorylation | regulation of clathrin-dependent endocytosis | regulation of localization | establishment of localization | membrane organization | cellular process | localization | establishment of localization in cell | regulation of cellular process | cellular component organization | phosphatase activity | cellular localization | protein modification process | macromolecule modification | protein tyrosine phosphatase activity | synaptic vesicle cycle | nitrogen compound metabolic process | phosphorus metabolic process | synaptic vesicle recycling | regulation of receptor-mediated endocytosis | phosphoprotein phosphatase activity | vesicle-mediated transport | phosphate-containing compound metabolic process | synaptic vesicle endocytosis | cellular protein complex disassembly | vesicle uncoating | protein metabolic process | import into cell | metabolic process | regulation of vesicle-mediated transport | endocytosis | clathrin-dependent endocytosis | organic substance metabolic process | protein depolymerization | synaptic vesicle uncoating | dephosphorylation | regulation of endocytosis | protein-containing complex disassembly | cellular protein metabolic process | receptor-mediated endocytosis | cellular protein modification process | regulation of transport | peptidyl-tyrosine dephosphorylation | clathrin coat disassembly | cellular metabolic process | regulation of cellular component organization | macromolecule metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | synapse | cell | cytoplasm | intracellular organelle | postsynapse | vesicle | postsynaptic density | asymmetric synapse | membrane-bounded organelle | organelle | postsynaptic specialization | cytosol | intracellular