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QuickView for DVL3 (gene)


Gene Symbol:
DVL3 Homo sapiens Homo sapiens
Full name:
dishevelled segment polarity protein 3
Synonyms:
DRS3, segment polarity protein dishevelled homolog DVL-3, dishevelled 3 (homologous to Drosophila dsh), dishevelled, dsh homolog 3
Genomic Location:
Chr 3: 185355978-185374008
Description:
This gene is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. The Drosophila dishevelled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation.
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 3
3q27.1





GO Molecular Function

beta-catenin binding | GTPase binding | Rho GTPase binding | enzyme binding | signaling receptor binding | Ras GTPase binding | frizzled binding | protein heterodimerization activity | protein binding | protein dimerization activity | Rac GTPase binding | G-protein coupled receptor binding | small GTPase binding | protease binding

GO Biological Process

regulation of JUN kinase activity | non-canonical Wnt signaling pathway via MAPK cascade | positive regulation of macromolecule biosynthetic process | positive regulation of cellular component organization | regulation of cell morphogenesis | regulation of neurogenesis | regulation of cellular localization | intracellular signal transduction | regulation of cell development | protein stabilization | regulation of localization | morphogenesis of an epithelium | negative regulation of cellular process | positive regulation of developmental process | regulation of MAP kinase activity | cell differentiation | nervous system development | response to drug | neurogenesis | positive regulation of phosphate metabolic process | generation of neurons | positive regulation of GTPase activity | positive regulation of cellular biosynthetic process | cellular process | epithelial tube morphogenesis | negative regulation of signaling | canonical Wnt signaling pathway | beta-catenin destruction complex disassembly | regulation of embryonic development | positive regulation of protein kinase activity | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | regulation of neuron projection development | regulation of canonical Wnt signaling pathway | tissue development | regulation of cell differentiation | regulation of cellular process | regulation of metabolic process | positive regulation of stress-activated MAPK cascade | positive regulation of cellular protein metabolic process | epithelium development | regulation of establishment of planar polarity | cellular component organization | positive regulation of stress-activated protein kinase signaling cascade | response to stimulus | regulation of cellular protein localization | embryonic epithelial tube formation | positive regulation of protein metabolic process | non-canonical Wnt signaling pathway via JNK cascade | tube morphogenesis | epithelial tube formation | positive regulation of protein serine/threonine kinase activity | positive regulation of RNA biosynthetic process | Wnt signaling pathway, planar cell polarity pathway | embryo development | cell-cell signaling | cell surface receptor signaling pathway involved in cell-cell signaling | regulation of nucleic acid-templated transcription | regulation of cellular response to stress | system development | regulation of signal transduction | Wnt signaling pathway | regulation of protein stability | positive regulation of neuron projection development | multicellular organism development | regulation of MAPK cascade | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | regulation of neuron differentiation | regulation of gene expression | neural tube closure | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of nitrogen compound metabolic process | positive regulation of JNK cascade | positive regulation of cell projection organization | positive regulation of intracellular signal transduction | neural tube formation | positive regulation of hydrolase activity | positive regulation of neuron projection arborization | positive regulation of cell differentiation | non-canonical Wnt signaling pathway | neural tube development | regulation of cellular protein metabolic process | regulation of GTPase activity | chordate embryonic development | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of protein metabolic process | positive regulation of signal transduction | regulation of protein phosphorylation | embryo development ending in birth or egg hatching | regulation of RNA metabolic process | embryonic morphogenesis | positive regulation of molecular function | positive regulation of protein modification process | tissue morphogenesis | regulation of kinase activity | regulation of animal organ morphogenesis | regulation of establishment of planar polarity involved in neural tube closure | regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | positive regulation of neurogenesis | positive regulation of cell development | regulation of RNA biosynthetic process | morphogenesis of embryonic epithelium | positive regulation of kinase activity | regulation of Wnt signaling pathway | regulation of phosphate metabolic process | regulation of JNK cascade | positive regulation of MAPK cascade | anatomical structure formation involved in morphogenesis | regulation of stress-activated MAPK cascade | regulation of cell communication | negative regulation of signal transduction | signaling | regulation of transcription, DNA-templated | protein-containing complex disassembly | positive regulation of phosphorylation | anatomical structure morphogenesis | positive regulation of MAP kinase activity | regulation of nervous system development | regulation of developmental process | developmental process | negative regulation of canonical Wnt signaling pathway | tube development | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | tube closure | tube formation | positive regulation of JUN kinase activity | positive regulation of metabolic process | negative regulation of Wnt signaling pathway | positive regulation of neuron differentiation | regulation of cell projection organization | regulation of protein localization | regulation of cellular component organization | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | planar cell polarity pathway involved in neural tube closure | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

chromosome | intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | chromatin | nuclear chromosome | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | nuclear chromatin | cytosol | intracellular