QuickView for ER1 (gene)

Gene Symbol:

MIER1 Homo sapiens

Full name:

MIER1 transcriptional regulator

Synonyms:

ER1, MI-ER1, mesoderm induction early response protein 1, mesoderm induction early response 1 homolog, mesoderm induction early response 1, transcriptional regulator

Genomic Location:

Chr 1: 67163230-67226890

Description:

This gene encodes a protein that was first identified in Xenopus laevis by its role in a mesoderm induction early response (MIER). The encoded protein functions as a transcriptional regulator. Alternatively spliced transcript variants encode multiple isoforms, some of which lack a C-terminal nuclear localization signal.

This gene encodes a protein that was first identified in Xenopus laevis by its role in a mesoderm induction early response (MIER). The encoded protein functions as a transcriptional regulator. Alternatively spliced transcript variants encode multiple isoforms, some of which lack a C-terminal nuclear localization signal.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CMYB_01 ,  TTTGCAC_MIR19A_MIR19B ,  TGANTCA_AP1_C ,  MAZ_Q6 ,  TGTGTGA_MIR377 ,  TTTGTAG_MIR520D ,  IPF1_Q4 ,  ATCMNTCCGY_UNKNOWN ,  TAAYNRNNTCC_UNKNOWN ,  TTGCACT_MIR130A_MIR301_MIR130B ,  HNF1_C ,  E2F1_Q4 ,  CTTTGTA_MIR524 ,  GGGAGGRR_MAZ_Q6 ,  TATCTGG_MIR488 ,  CDPCR3HD_01 ,  ATCATGA_MIR433 ,  TGCACTG_MIR148A_MIR152_MIR148B ,  CAGCTTT_MIR320 ,  ATTCTTT_MIR186 ,  GGGCGGR_SP1_Q6 ,  TCCAGAT_MIR5165P ,  SCGGAAGY_ELK1_02 ,  RGAGGAARY_PU1_Q6 ,  CTGCAGY_UNKNOWN ,  RCGCANGCGY_NRF1_Q6 ,  CRX_Q4 ,  ETF_Q6

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-130 ,  Predicted Gene Targets for miR-148 ,  Predicted Gene Targets for miR-186 ,  Predicted Gene Targets for miR-19 ,  Predicted Gene Targets for miR-299 ,  Predicted Gene Targets for miR-320 ,  Predicted Gene Targets for miR-377 ,  Predicted Gene Targets for miR-433-3p ,  Predicted Gene Targets for miR-488

Cytogenetic Map:

1p31.3

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