QuickView for FBXW12;jsessionid=773DEE7631D1151E1E7D194CE87AB126 (gene)
- Gene Symbol:
- FBXW12
Homo sapiens - Full name:
- F-box and WD repeat domain containing 12
- Synonyms:
- FBW12, FBXO12, FBXO35, F-box/WD repeat-containing protein 12, F-box and WD-40 domain protein 12, F-box and WD-40 domain-containing protein 12, F-box only protein 35, F-box- and WD40-repeat-containing protein
- Genomic Location:
- Chr 3: 48388713-48411194
- Description:
-
Members of the F-box protein family, such as FBXW12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets thro...
- Orthologs:
- Mus musculus , Rattus norvegicus , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
3p21.31
GO Molecular Function
catalytic activity | ubiquitin-like protein transferase activity | ubiquitin-protein transferase activity | transferase activity
GO Biological Process
cellular process | protein modification process | macromolecule modification | nitrogen compound metabolic process | protein modification by small protein conjugation | protein polyubiquitination | protein metabolic process | protein ubiquitination | metabolic process | ubiquitin-protein transferase activity | organic substance metabolic process | protein modification by small protein conjugation or removal | cellular protein metabolic process | cellular protein modification process | cellular metabolic process | post-translational protein modification | macromolecule metabolic process
GO Cellular Component
cell | cytoplasm | cytosol | intracellular
