QuickView for GFAP (gene)

Gene Symbol:

GFAP Homo sapiens

Full name:

glial fibrillary acidic protein

Synonyms:

ALXDRD, glial fibrillary acidic protein

Genomic Location:

Chr 17: 40338519-40348394

Description:

This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants ...

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This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

E12_Q6 ,  TGANTCA_AP1_C ,  SREBP1_02 ,  GCANCTGNY_MYOD_Q6 ,  AP1_Q6 ,  SREBP1_Q6 ,  TGACCTY_ERR1_Q2 ,  CACCCBINDINGFACTOR_Q6 ,  CAGGTG_E12_Q6 ,  AP1_01 ,  E47_02 ,  BACH2_01 ,  AP1_Q2_01 ,  AAAGACA_MIR511 ,  TGCCAAR_NF1_Q6 ,  BACH1_01 ,  SREBP_Q3 ,  TTCYNRGAA_STAT5B_01 ,  ER_Q6_02 ,  ER_Q6_01 ,  ER_Q6 ,  STAT5A_02

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Cytogenetic Map:

17q21.31

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