QuickView for GNAI1;jsessionid=A9E7E7073C569C800C19BEE3DD9A17E6 (gene)

Gene Symbol:

GNAI1 Homo sapiens

Full name:

G protein subunit alpha i1

Synonyms:

Gi, guanine nucleotide-binding protein G(i) subunit alpha-1, Gi1 protein alpha subunit, adenylate cyclase-inhibiting G alpha protein, guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1

Genomic Location:

Chr 7: 79602076-79686661

Description:

Guanine nucleotide binding proteins are heterotrimeric signal-transducing molecules consisting of alpha, beta, and gamma subunits. The alpha subunit binds guanine nucleotide, can hydrolyze GTP, and can interact with other proteins. The protein encoded by this gene represents the alpha subunit of an inhibitory complex. The encoded protein is part of...

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Guanine nucleotide binding proteins are heterotrimeric signal-transducing molecules consisting of alpha, beta, and gamma subunits. The alpha subunit binds guanine nucleotide, can hydrolyze GTP, and can interact with other proteins. The protein encoded by this gene represents the alpha subunit of an inhibitory complex. The encoded protein is part of a complex that responds to beta-adrenergic signals by inhibiting adenylate cyclase. Two transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Bos taurus ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGANTCA_AP1_C ,  TTANTCA_UNKNOWN ,  TTTTGAG_MIR373 ,  YNTTTNNNANGCARM_UNKNOWN ,  IPF1_Q4 ,  AP1_Q6 ,  CTTTGTA_MIR524 ,  TGTATGA_MIR4853P ,  AP1FJ_Q2 ,  NKX62_Q2 ,  CTTTAAR_UNKNOWN ,  AP1_Q4 ,  GTGCCTT_MIR506 ,  BACH1_01 ,  ATATGCA_MIR448 ,  CTGCAGY_UNKNOWN ,  AP1_Q2 ,  ER_Q6_01 ,  AACTTT_UNKNOWN ,  AP1_Q4_01 ,  HOX13_01 ,  AAGCACA_MIR218 ,  TCF11_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-181 ,  Predicted Gene Targets for miR-19 ,  Predicted Gene Targets for miR-218 ,  Predicted Gene Targets for miR-320 ,  Predicted Gene Targets for miR-448 ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-384 ,  Predicted Gene Targets for miR-485-3p

Cytogenetic Map:

7q21.11

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