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QuickView for GPI (gene)

Gene Symbol:
GPI Homo sapiens Homo sapiens
Full name:
glucose-6-phosphate isomerase
AMF, GNPI, NLK, PGI, PHI, SA-36, SA36, glucose-6-phosphate isomerase, autocrine motility factor, hexose monophosphate isomerase, hexosephosphate isomerase, neuroleukin, oxoisomerase, phosphoglucose isomerase, phosphohexomutase, phosphohexose isomerase, phosphosaccharomutase, sperm antigen-36
Genomic Location:
Chr 19: 39547909-39583076
This gene encodes a member of the glucose phosphate isomerase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In the cytoplasm, the gene product functions as a glycolytic enzyme (glucose-6-phosphate isomerase) that interconverts glucose-6-phosphate...
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Danio rerio Schizosaccharomyces pombe Bos taurus Gallus gallus Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 19

GO Molecular Function

isomerase activity | enzyme binding | signaling receptor binding | monosaccharide binding | molecular function regulator | catalytic activity | glucose-6-phosphate isomerase activity | ubiquitin-like protein ligase binding | intramolecular oxidoreductase activity | carbohydrate binding | protein binding | receptor regulator activity | ubiquitin protein ligase binding | growth factor activity | receptor ligand activity | cytokine activity | intramolecular transferase activity | small molecule binding

GO Biological Process

purine ribonucleotide metabolic process | purine ribonucleoside monophosphate biosynthetic process | positive regulation of locomotion | exocytosis | nucleoside phosphate catabolic process | neutrophil activation | glycolytic process | regulation of localization | establishment of localization | regulation of immune system process | glucose metabolic process | nicotinamide nucleotide biosynthetic process | generation of precursor metabolites and energy | organophosphate catabolic process | positive regulation of cellular component movement | positive regulation of protein secretion | regulation of immunoglobulin secretion | cellular process | secretion | organic substance catabolic process | leukocyte degranulation | regulation of cell motility | localization | nucleotide metabolic process | positive regulation of immune effector process | NADH regeneration | ribose phosphate metabolic process | purine nucleotide biosynthetic process | hemostasis | nucleoside triphosphate metabolic process | ribonucleotide metabolic process | carbohydrate catabolic process | regulation of cellular process | leukocyte activation | catabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | positive regulation of epithelial cell migration | regulation of peptide secretion | response to stimulus | purine nucleotide metabolic process | monocarboxylic acid metabolic process | neutrophil degranulation | positive regulation of immune system process | positive regulation of immunoglobulin production | leukocyte activation involved in immune response | cellular nitrogen compound biosynthetic process | secretion by cell | cellular nitrogen compound metabolic process | carbohydrate derivative biosynthetic process | regulation of protein transport | cofactor metabolic process | regulation of peptide transport | cellular biosynthetic process | nucleobase-containing compound catabolic process | molecular function regulator | nucleotide biosynthetic process | positive regulation of peptide secretion | NADH metabolic process | ATP biosynthetic process | nitrogen compound metabolic process | regulation of signal transduction | coenzyme biosynthetic process | phosphorus metabolic process | ribonucleoside monophosphate biosynthetic process | leukocyte mediated immunity | NAD biosynthetic process | positive regulation of secretion | organophosphate metabolic process | hexose biosynthetic process | nucleotide phosphorylation | cofactor biosynthetic process | regulation of cell migration | monosaccharide metabolic process | small molecule metabolic process | vesicle-mediated transport | regulation of cellular component movement | regulation of endothelial cell migration | nucleobase-containing small molecule metabolic process | positive regulation of cell migration | carbohydrate biosynthetic process | biosynthetic process | pyruvate metabolic process | aromatic compound biosynthetic process | phosphorylation | purine ribonucleotide biosynthetic process | regulated exocytosis | carbohydrate metabolic process | nucleotide catabolic process | nucleoside triphosphate biosynthetic process | phosphate-containing compound metabolic process | humoral immune response | cell activation involved in immune response | myeloid cell activation involved in immune response | aromatic compound catabolic process | neutrophil activation involved in immune response | positive regulation of establishment of protein localization | regulation of locomotion | positive regulation of transport | drug metabolic process | carboxylic acid metabolic process | pyridine nucleotide biosynthetic process | glycolytic process through glucose-6-phosphate | regulation of signaling receptor activity | receptor regulator activity | regulation of establishment of protein localization | nucleoside diphosphate metabolic process | growth factor activity | metabolic process | hexose metabolic process | regulation of body fluid levels | oxidation-reduction process | regulation of secretion | receptor ligand activity | gluconeogenesis | immune response | nucleobase-containing compound metabolic process | cytokine activity | organic substance metabolic process | regulation of protein secretion | glucose 6-phosphate metabolic process | glycolytic process through fructose-6-phosphate | ATP generation from ADP | positive regulation of endothelial cell migration | cell activation | pyruvate biosynthetic process | positive regulation of protein transport | regulation of epithelial cell migration | ADP metabolic process | regulation of cell communication | regulation of immunoglobulin production | ribose phosphate biosynthetic process | organic acid metabolic process | glucose catabolic process | positive regulation of immunoglobulin secretion | nicotinamide nucleotide metabolic process | NAD metabolic process | carbohydrate derivative metabolic process | regulation of transport | neutrophil mediated immunity | canonical glycolysis | heterocycle metabolic process | immune system process | cellular metabolic process | ATP metabolic process | regulation of protein localization | positive regulation of cell motility | nucleoside diphosphate phosphorylation | nucleoside monophosphate biosynthetic process | regulation of signaling

GO Cellular Component

secretory granule | intracellular membrane-bounded organelle | cytoplasmic vesicle | cell | nuclear lumen | cytoplasmic vesicle lumen | cytoplasm | intracellular organelle | ficolin-1-rich granule lumen | secretory vesicle | endomembrane system | nucleoplasm | plasma membrane | vesicle | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | nucleus | organelle | extracellular space | cell periphery | membrane-enclosed lumen | secretory granule lumen | cytosol | intracellular vesicle | intracellular | membrane | vesicle lumen