QuickView for GPLD1;jsessionid=30CDE4AC1253CFE4D86FD120B5ADCF7A (gene)

Gene Symbol:

GPLD1 Homo sapiens

Full name:

glycosylphosphatidylinositol specific phospholipase D1

Synonyms:

GPIPLD, GPIPLDM, PIGPLD, PIGPLD1, PLD, phosphatidylinositol-glycan-specific phospholipase D, GPI-PLD, GPI-specific phospholipase D, PI-G PLD, glycoprotein phospholipase D

Genomic Location:

Chr 6: 24536384-24597829

Description:

Many proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI-anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in ...

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Many proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI-anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma membrane.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

YTATTTTNR_MEF2_02 ,  DBP_Q6 ,  LMO2COM_02 ,  TGCCAAR_NF1_Q6 ,  TGTTTGY_HNF3_Q6 ,  CEBP_Q3 ,  TTGTTT_FOXO4_01 ,  CEBP_C ,  P300_01 ,  CEBPGAMMA_Q6

Cytogenetic Map:

6p22.3

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