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QuickView for GTF2H4;jsessionid=71F2100AAD66FBE7E3B0DF65CA573317 (gene)


Gene Symbol:
GTF2H4 Homo sapiens Homo sapiens
Full name:
general transcription factor IIH subunit 4
Synonyms:
P52, TFB2, TFIIH, general transcription factor IIH subunit 4, BTF2 p52, TFIIH basal transcription factor complex p52 subunit, basic transcription factor 2 52 kDa subunit, general transcription factor IIH polypeptide 4, general transcription factor IIH, polypeptide 4, 52kDa
Genomic Location:
Chr 6: 30983956-30989859
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Bos taurus Schizosaccharomyces pombe Danio rerio Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Cytogenetic Map:
chr 6
6p21.33


Transcripts Names
NM_001517
Protein Names
Q92759
Q76KU4
A0A1U9X7S4



GO Molecular Function

nucleic acid binding | ATP-dependent DNA helicase activity | hydrolase activity | protein serine/threonine kinase activity | ATPase activity | pyrophosphatase activity | RNA polymerase II CTD heptapeptide repeat kinase activity | catalytic activity | nucleoside-triphosphatase activity | ATPase activity, coupled | DNA binding | ATP-dependent helicase activity | organic cyclic compound binding | DNA helicase activity | protein binding | double-stranded DNA binding | DNA-binding transcription factor activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | hydrolase activity, acting on acid anhydrides | protein kinase activity | transferase activity | DNA-dependent ATPase activity | helicase activity | kinase activity | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

GO Biological Process

RNA metabolic process | transcription by RNA polymerase II | DNA-templated transcription, initiation | RNA processing | positive regulation of cellular component organization | transcription initiation from RNA polymerase I promoter | cellular process | 7-methylguanosine mRNA capping | global genome nucleotide-excision repair | DNA geometric change | regulation of cellular process | regulation of metabolic process | regulation of protein complex assembly | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | ATP-dependent DNA helicase activity | response to stimulus | response to stress | transcription by RNA polymerase I | cellular nitrogen compound biosynthetic process | protein serine/threonine kinase activity | protein-DNA complex assembly | cellular nitrogen compound metabolic process | nucleic acid phosphodiester bond hydrolysis | cellular component assembly | protein modification process | mRNA metabolic process | RNA polymerase II CTD heptapeptide repeat kinase activity | cellular biosynthetic process | macromolecule modification | DNA repair | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | phosphorus metabolic process | cellular response to DNA damage stimulus | nucleotide-excision repair, DNA incision, 5'-to lesion | regulation of gene expression | cellular response to stress | regulation of nitrogen compound metabolic process | positive regulation of protein complex assembly | regulation of transcription by RNA polymerase II | phosphorylation of RNA polymerase II C-terminal domain | biosynthetic process | aromatic compound biosynthetic process | phosphorylation | cellular protein-containing complex assembly | nucleotide-excision repair, preincision complex stabilization | transcription elongation from RNA polymerase II promoter | protein phosphorylation | phosphate-containing compound metabolic process | DNA duplex unwinding | regulation of cellular metabolic process | regulation of RNA metabolic process | DNA-templated transcription, termination | DNA helicase activity | protein-containing complex assembly | protein metabolic process | DNA-binding transcription factor activity | DNA metabolic process | nucleotide-excision repair, DNA incision | metabolic process | nucleotide-excision repair | regulation of RNA biosynthetic process | nucleobase-containing compound metabolic process | protein kinase activity | positive regulation of cellular component biogenesis | organic substance metabolic process | gene expression | transcription initiation from RNA polymerase II promoter | transcription, DNA-templated | transcription-coupled nucleotide-excision repair | regulation of transcription, DNA-templated | cellular protein metabolic process | cellular macromolecule biosynthetic process | kinase activity | organelle organization | cellular protein modification process | 7-methylguanosine RNA capping | DNA conformation change | heterocycle metabolic process | chromosome organization | cellular metabolic process | mRNA processing | regulation of cellular component organization | termination of RNA polymerase I transcription | nucleotide-excision repair, preincision complex assembly | macromolecule metabolic process | DNA-templated transcription, elongation

GO Cellular Component

nuclear transcription factor complex | intracellular membrane-bounded organelle | catalytic complex | RNA polymerase II transcription factor complex | protein kinase complex | cell | nuclear lumen | transcription factor complex | intracellular organelle | nuclear body | carboxy-terminal domain protein kinase complex | protein-containing complex | nucleoplasm | nuclear speck | transferase complex | core TFIIH complex portion of holo TFIIH complex | serine/threonine protein kinase complex | membrane-bounded organelle | holo TFIIH complex | nucleus | organelle | nuclear DNA-directed RNA polymerase complex | transcription factor TFIID complex | RNA polymerase complex | membrane-enclosed lumen | core TFIIH complex | intracellular | RNA polymerase II, holoenzyme