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QuickView for HB-EGF (gene)


Gene Symbol:
Hbegf Rattus norvegicus Rattus norvegicus
Full name:
heparin-binding EGF-like growth factor
Synonyms:
Dtr, GFHB, Hb-egf, Hegfl, proheparin-binding EGF-like growth factor, Diphtheria toxin receptor (heparin binding epidermal growth factor - like growth factor), heparin binding epidermal growth factor-like growth factor, heparin-binding epidermal -growth - like growth factor, heparin-binding epidermal -growth factor
Genomic Location:
Chr 18: 29143567-29153944
Description:
activates epidermal growth factor receptor mediated signaling; contributes to neuronal survival; may play a role in neurogenesis during ventral midbrain development
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Gallus gallus Bos taurus Canis lupus familiaris Pan troglodytes Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):


Transcripts Names
NM_012945
Protein Names
Q06175



GO Molecular Function

signaling receptor binding | carbohydrate derivative binding | molecular function regulator | anion binding | ion binding | heparin binding | protein binding | receptor regulator activity | growth factor activity | receptor ligand activity | glycosaminoglycan binding | epidermal growth factor receptor binding | growth factor receptor binding

GO Biological Process

positive regulation of smooth muscle cell proliferation | positive regulation of locomotion | cell motility | regulation of localization | morphogenesis of an epithelium | positive regulation of peptidyl-tyrosine phosphorylation | negative regulation of cellular process | nervous system development | positive regulation of phosphate metabolic process | positive regulation of cellular component movement | cellular process | positive regulation of keratinocyte migration | regulation of cell motility | localization | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | tissue development | regulation of protein kinase B signaling | regulation of cellular process | positive regulation of cell growth | regulation of metabolic process | epidermal growth factor receptor signaling pathway | positive regulation of cellular protein metabolic process | epithelium development | positive regulation of epithelial cell migration | response to stimulus | regulation of glycoprotein biosynthetic process | wound healing, spreading of cells | regulation of peptidyl-tyrosine phosphorylation | positive regulation of protein metabolic process | response to stress | regulation of cell proliferation | regulation of blood circulation | ERBB signaling pathway | negative regulation of metabolic process | regulation of wound healing | cell chemotaxis | molecular function regulator | epiboly | locomotion | system development | positive regulation of response to wounding | regulation of signal transduction | multicellular organism development | cell migration | positive regulation of protein kinase B signaling | regulation of phosphorylation | wound healing | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of nitrogen compound metabolic process | regulation of cell migration | enzyme linked receptor protein signaling pathway | positive regulation of intracellular signal transduction | regulation of cellular component movement | morphogenesis of an epithelial sheet | positive regulation of cell migration | regulation of cellular protein metabolic process | regulation of heart contraction | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | positive regulation of signal transduction | positive regulation of cell proliferation | regulation of protein phosphorylation | regulation of locomotion | regulation of signaling receptor activity | receptor regulator activity | positive regulation of protein modification process | regulation of growth | tissue morphogenesis | response to wounding | regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | growth factor activity | receptor ligand activity | negative regulation of glycoprotein metabolic process | negative regulation of biosynthetic process | regulation of phosphate metabolic process | positive regulation of wound healing | negative regulation of protein metabolic process | regulation of epithelial cell migration | regulation of response to wounding | regulation of cell communication | signaling | positive regulation of growth | positive regulation of phosphorylation | anatomical structure morphogenesis | developmental process | regulation of cell growth | transmembrane receptor protein tyrosine kinase signaling pathway | positive regulation of metabolic process | negative regulation of elastin biosynthetic process | wound healing, spreading of epidermal cells | regulation of smooth muscle cell proliferation | positive regulation of cell motility | chemotaxis | regulation of cellular component organization | positive regulation of signaling | signal transduction | regulation of signaling | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

integral component of membrane | cell | intrinsic component of membrane | plasma membrane | integral component of plasma membrane | extracellular region | extracellular space | cell periphery | cell surface | membrane | intrinsic component of plasma membrane