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QuickView for ID3 (gene)


Gene Symbol:
ID3 Homo sapiens Homo sapiens
Full name:
inhibitor of DNA binding 3, HLH protein
Synonyms:
HEIR-1, bHLHb25, DNA-binding protein inhibitor ID-3, ID-like protein inhibitor HLH 1R21, class B basic helix-loop-helix protein 25, helix-loop-helix protein HEIR-1, inhibitor of DNA binding 3, dominant negative helix-loop-helix protein, inhibitor of differentiation 3
Genomic Location:
Chr 1: 23756996-23758909
Description:
The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with other HLH proteins. However, the encoded protein lacks a basic DNA-binding domain and therefore inhibits the DNA binding of any HLH protein with which it interacts.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Canis lupus familiaris Bos taurus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
NFAT_Q4_01 TFIIA_Q6 PR_02 CEBPA_01 OCT1_B RYTTCCTG_ETS2_B OCT1_01 E2F1_Q4_01 E2F4DP1_01 GTGACTT_MIR224
miRNA binding sites
(Source: TargetScan):
miRNA binding sites
(Source: miRecords):
Cytogenetic Map:
chr 1
1p36.12


Transcripts Names
NM_002167
Protein Names
Q02535
A8K1T8
O75641



GO Molecular Function

fatty acid binding | transcription factor activity, transcription factor binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcription factor activity, RNA polymerase II transcription factor binding | carboxylic acid binding | lipid binding | transcriptional repressor activity, RNA polymerase II transcription factor binding | leptomycin B binding | protein domain specific binding | anion binding | transcription corepressor activity | ion binding | organic cyclic compound binding | protein binding | DNA-binding transcription factor activity | transcription factor binding | RNA polymerase II transcription factor binding | protein dimerization activity | transcription coregulator activity | organic acid binding | heterocyclic compound binding | small molecule binding

GO Biological Process

RNA metabolic process | transcription factor activity, transcription factor binding | regulation of neurogenesis | positive regulation of apoptotic process | regulation of cell development | regulation of programmed cell death | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | negative regulation of RNA biosynthetic process | cell differentiation | nervous system development | neurogenesis | regulation of DNA replication | generation of neurons | response to antibiotic | cellular process | odontogenesis | negative regulation of nucleic acid-templated transcription | regulation of cell cycle | transcription factor activity, RNA polymerase II transcription factor binding | negative regulation of cellular metabolic process | tissue development | regulation of binding | regulation of cell differentiation | muscle structure development | regulation of cellular process | regulation of osteoblast differentiation | regulation of apoptotic process | cellular response to lipid | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | epithelium development | cellular aromatic compound metabolic process | urogenital system development | response to stimulus | transcriptional repressor activity, RNA polymerase II transcription factor binding | response to stress | cellular nitrogen compound biosynthetic process | circadian rhythm | rhythmic process | cellular nitrogen compound metabolic process | regulation of DNA binding | cellular response to organic cyclic compound | negative regulation of metabolic process | cellular biosynthetic process | kidney development | embryo development | regulation of nucleic acid-templated transcription | negative regulation of osteoblast differentiation | system development | nitrogen compound metabolic process | cellular response to antibiotic | multicellular organism development | response to fatty acid | regulation of ossification | regulation of neuron differentiation | regulation of gene expression | response to lipid | cellular response to leptomycin B | animal organ morphogenesis | regulation of nitrogen compound metabolic process | negative regulation of DNA-binding transcription factor activity | negative regulation of DNA binding | transcription corepressor activity | regulation of transcription by RNA polymerase II | negative regulation of binding | negative regulation of myoblast differentiation | biosynthetic process | aromatic compound biosynthetic process | regulation of cellular metabolic process | metanephros development | heart development | regulation of RNA metabolic process | renal system development | cellular response to fatty acid | notochord development | neuron differentiation | DNA-binding transcription factor activity | response to organic substance | response to wounding | negative regulation of ossification | regulation of DNA-binding transcription factor activity | anatomical structure development | metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | embryonic organ development | regulation of myoblast differentiation | positive regulation of cell death | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | negative regulation of neuron differentiation | gene expression | positive regulation of programmed cell death | transcription, DNA-templated | negative regulation of molecular function | regulation of transcription, DNA-templated | response to organic cyclic compound | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | regulation of nervous system development | regulation of developmental process | developmental process | negative regulation of transcription by RNA polymerase II | transcription coregulator activity | epithelial cell differentiation | heterocycle metabolic process | central nervous system development | cellular metabolic process | cellular response to organic substance | regulation of cell death | negative regulation of cell development | circulatory system development | negative regulation of cell differentiation | muscle organ development | macromolecule metabolic process | negative regulation of neurogenesis | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | membrane-bounded organelle | nucleus | organelle | intracellular