QuickView for ING1 (gene)

Gene Symbol:

ING1 Homo sapiens

Full name:

inhibitor of growth family member 1

Synonyms:

p24ING1c, p33, p33ING1, p33ING1b, p47, p47ING1a, inhibitor of growth protein 1, growth inhibitor ING1, growth inhibitory protein ING1, tumor suppressor ING1

Genomic Location:

Chr 13: 110163084-110171422

Description:

This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple al...

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This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

RTAAACA_FREAC2_01 ,  OCT1_05 ,  P53_DECAMER_Q2 ,  OCT1_01 ,  YATGNWAAT_OCT_C ,  TTAYRTAA_E4BP4_01 ,  OCT_C ,  TATAAA_TATA_01 ,  HLF_01 ,  POU3F2_02 ,  CCTGCTG_MIR214 ,  AACTTT_UNKNOWN

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-138 ,  Predicted Gene Targets for miR-214 ,  Predicted Gene Targets for miR-124u

Cytogenetic Map:

13q34

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