QuickView for IRA1 (gene)
- Gene Symbol:
- IRA1
Saccharomyces cerevisiae - Full name:
- GTPase-activating protein that negatively regulates RAS by converting it from the GTP- to the GDP-bound inactive form, required for reducing cAMP levels under nutrient limiting conditions, mediates membrane association of adenylate cyclase
- Synonyms:
- GLC1, IRA1, Ira1, IRA1, PPD1, YBR140C
- Genomic Location:
- Chr II: 517344-526622
- External Links:
- Entrez Gene
GO Molecular Function
enzyme activator activity | GTPase activator activity | GTPase regulator activity | molecular function regulator | enzyme regulator activity
GO Biological Process
enzyme activator activity | negative regulation of cellular process | positive regulation of GTPase activity | cellular process | negative regulation of signaling | GTPase activator activity | positive regulation of catalytic activity | regulation of cellular process | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway | response to stimulus | GTPase regulator activity | G-protein coupled receptor signaling pathway | molecular function regulator | regulation of signal transduction | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | regulation of catalytic activity | regulation of small GTPase mediated signal transduction | positive regulation of hydrolase activity | regulation of GTPase activity | regulation of cyclase activity | cell communication | positive regulation of molecular function | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | negative regulation of small GTPase mediated signal transduction | negative regulation of Ras protein signal transduction | regulation of adenylate cyclase activity | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | regulation of cell communication | negative regulation of signal transduction | signaling | enzyme regulator activity | regulation of Ras protein signal transduction | signal transduction | regulation of signaling
GO Cellular Component
integral component of membrane | intracellular membrane-bounded organelle | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | mitochondrion | membrane-bounded organelle | organelle | intracellular | membrane
