Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward

QuickView for Isoetharine (compound)

Name: Isoetharine
PubChem Compound ID: 23702
Description: Adrenergic beta-2 agonist used as bronchodilator for emphysema, bronchitis and asthma.
Molecular formula: C14H25NO6S
Molecular weight: 335.417 g/mol
1,2-Benzenediol, 4-(1-hydroxy-2-((1-methylethyl)amino)-butyl)-, methanesulfonate (salt); 4-(1-HYDROXY-2-[(1-METHYLETHYL)AMINO]BUTYL)-1,2-BENZENEDIOL METHANESULFONATE SALT; MLS000069674; 3,4-Dihydroxy-alpha-(1-(isopropylamino)propyl)benzyl alcohol methanesulfonate (salt); 7279-75-6; EU-0100671; Isoetarine mesilate; Isoetharine mesylate salt; Isoetharine mesylate [USAN:BAN]; EINECS 230-695-8.
show more »
Name: Isoetharine
Name (isomeric): DB00221
Drug Type: small molecule
Description: Adrenergic beta-2 agonist used as bronchodilator for emphysema, bronchitis and asthma.
Isoetharine mesylate; Isoetarinum [INN-Latin]; Isoetharine Hcl; Isoetarina [INN-Spanish]
Brand: Neoisuprel, Bronkometer, Bronkosol, Dey-Lute Isoetharine, Isoetarine, Dilabron, Etyprenaline, Isoetharine HCl S/F, Isoetarin, Beta-2
Category: Adrenergic beta-Agonists, Bronchodilator Agents
CAS number: 530-08-5
Indication: For the treatment of asthma, wheezing, and chronic asthmatic bronchitis.
Pharmacology: Isoetharine is a relatively selective beta2-adrenergic bronchodilator. Isoetharine is indicated for the relief of bronchospasm associated with chronic obstructive pulmonary disease. Adrenergic bronchodilators are breathed in through the mouth to open up the bronchial tubes (air passages) of the lungs.
Mechanism of Action:
The pharmacologic effects of isoetharine are attributable to stimulation through beta-adrenergic receptors of intracellular adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic AMP. Increased cyclic AMP levels are associated with relaxation of bronchial smooth muscle and inhibition of release of mediato...
show more »
Toxicity: Signs of overdose include tachycardia, palpitations, nausea, headache, and epinephrine-like side effects.
Affected organisms: Humans and other mammals
Drug interaction:
EntacaponeEntacapone increases the effect and toxicity of the sympathomimetic, isoetharine.