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QuickView for KLHL20;jsessionid=8CC9733B90F37854FE96C51D48951A1B (gene)


Gene Symbol:
KLHL20 Homo sapiens Homo sapiens
Full name:
kelch like family member 20
Synonyms:
KHLHX, KLEIP, KLHLX, kelch-like protein 20, Kelch motif containing protein, kelch-like ECT2-interacting protein, kelch-like protein X
Genomic Location:
Chr 1: 171950703-172022463
Description:
The protein encoded by this gene is a member of the kelch family of proteins, which is characterized by a 44-56 amino acid repeat motif. The kelch motif appears in many different polypeptide contexts and contains multiple potential protein-protein contact sites. Members of this family are present both throughout the cell and extracellularly, with d...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 1
1q25.1





GO Molecular Function

actin binding | cytokine binding | catalytic activity | ubiquitin-like protein transferase activity | cytoskeletal protein binding | interferon-gamma binding | protein binding | ubiquitin-protein transferase activity | transferase activity

GO Biological Process

response to cytokine | proteolysis | regulation of programmed cell death | establishment of localization | negative regulation of cellular process | intracellular transport | cellular process | organic substance catabolic process | localization | proteolysis involved in cellular protein catabolic process | protein transport | macromolecule localization | negative regulation of apoptotic process | establishment of localization in cell | cytosolic transport | regulation of cellular process | regulation of apoptotic process | catabolic process | cellular component organization | Golgi to endosome transport | response to stimulus | cellular protein catabolic process | cellular localization | proteasomal protein catabolic process | protein modification process | macromolecule modification | nitrogen compound metabolic process | post-Golgi vesicle-mediated transport | organic substance transport | protein catabolic process | protein modification by small protein conjugation | peptide transport | vesicle-mediated transport | response to interferon-alpha | Golgi vesicle transport | proteasome-mediated ubiquitin-dependent protein catabolic process | protein polyubiquitination | protein metabolic process | response to organic substance | protein ubiquitination | cellular macromolecule catabolic process | metabolic process | ubiquitin-protein transferase activity | negative regulation of programmed cell death | amide transport | protein K33-linked ubiquitination | organic substance metabolic process | protein modification by small protein conjugation or removal | cytoskeleton organization | establishment of protein localization | ubiquitin-dependent protein catabolic process | organonitrogen compound catabolic process | protein localization | cellular protein metabolic process | organelle organization | cellular protein modification process | cellular metabolic process | regulation of cell death | modification-dependent protein catabolic process | negative regulation of cell death | post-translational protein modification | macromolecule metabolic process

GO Cellular Component

dendrite | intracellular membrane-bounded organelle | catalytic complex | neuron projection | somatodendritic compartment | cell | nuclear lumen | Cul3-RING ubiquitin ligase complex | cytoplasm | intracellular organelle | actin cytoskeleton | ubiquitin ligase complex | nuclear body | dendritic tree | Golgi apparatus | protein-containing complex | cell projection | PML body | endomembrane system | nucleoplasm | transferase complex | perinuclear region of cytoplasm | cullin-RING ubiquitin ligase complex | membrane-bounded organelle | nucleus | organelle | axon | membrane-enclosed lumen | trans-Golgi network | cytosol | cytoskeleton | intracellular