QuickView for MRPS14;jsessionid=5486FE47787FBFFD390CAC015BD13128 (gene)

Gene Symbol:

MRPS14 Homo sapiens

Full name:

mitochondrial ribosomal protein S14

Synonyms:

DJ262D12.2, HSMRPS14, MRP-S14, S14mt, 28S ribosomal protein S14, mitochondrial, mitochondrial 28S ribosomal protein S14, mitochondrial small ribosomal subunit protein uS14m

Genomic Location:

Chr 1: 173249751-173259184

Description:

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Anothe...

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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S14P family. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Gallus gallus ,  Bos taurus ,  Canis lupus familiaris ,  Pan troglodytes ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GGGCGGR_SP1_Q6

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-27

Cytogenetic Map:

1q25.1

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