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QuickView for NKX2-3;jsessionid=51F396442FA66EFEA3D841B83F89D168 (gene)


Gene Symbol:
NKX2-3 Homo sapiens Homo sapiens
Full name:
NK2 homeobox 3
Synonyms:
CSX3, NK2.3, NKX2.3, NKX2C, NKX4-3, homeobox protein Nkx-2.3, NK2 transcription factor related, locus 3, homeobox protein NK-2 homolog C
Genomic Location:
Chr 10: 101282680-101286271
Description:
This gene encodes a homeodomain-containing transcription factor. The encoded protein is a member of the NKX family of homeodomain transcription factors. Studies of similar proteins in mouse and rat have indicated a potential role in cellular differentiation.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Bos taurus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 10
10q24.2


Transcripts Names
NM_145285
XM_011539370
Protein Names
B4DUZ4
Q9NYS6
Q8TAU0



GO Molecular Function

sequence-specific DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | nucleic acid binding | DNA binding | organic cyclic compound binding | DNA-binding transcription factor activity | heterocyclic compound binding

GO Biological Process

RNA metabolic process | leukocyte homeostasis | positive regulation of macromolecule biosynthetic process | CD4-positive, alpha-beta T cell differentiation | mucosal-associated lymphoid tissue development | cell motility | CD4-positive, alpha-beta T cell activation | myeloid cell differentiation | RNA polymerase II transcription factor activity, sequence-specific DNA binding | cell differentiation | B cell differentiation | positive regulation of cellular biosynthetic process | cellular process | lymphocyte differentiation | localization | odontogenesis | triglyceride metabolic process | immune system development | digestive tract morphogenesis | positive regulation of nitrogen compound metabolic process | tissue development | regulation of cellular process | leukocyte activation | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular lipid metabolic process | T cell activation | response to stimulus | gland morphogenesis | leukocyte activation involved in immune response | mature B cell differentiation | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | tube morphogenesis | post-embryonic digestive tract morphogenesis | macrophage differentiation | cellular nitrogen compound metabolic process | positive regulation of RNA biosynthetic process | hemopoiesis | cellular biosynthetic process | leukocyte migration | regulation of nucleic acid-templated transcription | leukocyte differentiation | locomotion | system development | nitrogen compound metabolic process | multicellular organism development | cell migration | spleen development | lipid metabolic process | regulation of gene expression | myeloid leukocyte differentiation | positive regulation of cellular metabolic process | animal organ morphogenesis | regulation of nitrogen compound metabolic process | post-embryonic animal morphogenesis | regulation of transcription by RNA polymerase II | alpha-beta T cell differentiation | mature B cell differentiation involved in immune response | homeostasis of number of cells | B cell activation | biosynthetic process | aromatic compound biosynthetic process | digestive tract development | plasma cell differentiation | post-embryonic development | regulation of cellular metabolic process | odontogenesis of dentin-containing tooth | cell activation involved in immune response | homeostatic process | glycerolipid metabolic process | regulation of RNA metabolic process | lymphocyte activation | lymph node development | T cell differentiation | DNA-binding transcription factor activity | gland development | neutral lipid metabolic process | digestive system development | anatomical structure development | metabolic process | regulation of RNA biosynthetic process | immune response | nucleobase-containing compound metabolic process | organic substance metabolic process | animal organ development | gene expression | alpha-beta T cell activation | transcription, DNA-templated | cell activation | regulation of transcription, DNA-templated | B cell activation involved in immune response | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | Peyer's patch development | developmental process | tube development | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | positive regulation of metabolic process | immune system process | cellular metabolic process | hematopoietic or lymphoid organ development | acylglycerol metabolic process | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | cell | intracellular organelle | membrane-bounded organelle | nucleus | organelle | intracellular