QuickView for NPFF;jsessionid=8627D5860C7A43D9D79BFCDA45BB0DFB (gene)

Gene Symbol:

NPFF Homo sapiens

Full name:

neuropeptide FF-amide peptide precursor

Synonyms:

FMRFAL, pro-FMRFamide-related neuropeptide FF

Genomic Location:

Chr 12: 52186741-52187689

Description:

This gene encodes a member of the FMRFamide related peptide (FARP) family of neuropeptides. The encoded preproprotein is proteolytically processed to generate multiple amidated peptides. These peptides may play a role in the regulation of heart rate and blood pressure and the modulation of morphine-induced antinociception. Patients with hypertensio...

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This gene encodes a member of the FMRFamide related peptide (FARP) family of neuropeptides. The encoded preproprotein is proteolytically processed to generate multiple amidated peptides. These peptides may play a role in the regulation of heart rate and blood pressure and the modulation of morphine-induced antinociception. Patients with hypertension exhibit decreased expression of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

RYCACNNRNNRNCAG_UNKNOWN

Cytogenetic Map:

12q13.13

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