QuickView for PARK7;jsessionid=07F539A4EF3EB49725BCB8C1946DC6FD (gene)

GO Molecular Function

L-dopa decarboxylase activator activity | cytokine binding | kinase binding | enzyme activator activity | transcription regulatory region DNA binding | core promoter binding | cadherin binding | cation binding | antioxidant activity | repressing transcription factor binding | hormone receptor binding | enzyme binding | nucleic acid binding | mRNA binding | superoxide dismutase copper chaperone activity | signaling receptor binding | hydrolase activity | single-stranded DNA binding | small protein activating enzyme binding | hydro-lyase activity | ubiquitin-specific protease binding | lyase activity | molecular function regulator | catalytic activity | mercury ion binding | androgen receptor binding | DNA binding | copper chaperone activity | identical protein binding | nuclear hormone receptor binding | scaffold protein binding | peroxiredoxin activity | ion binding | organic cyclic compound binding | cuprous ion binding | copper ion binding | cell adhesion molecule binding | transcription coactivator activity | protein binding | protein homodimerization activity | double-stranded DNA binding | transcription factor binding | tyrosine 3-monooxygenase activator activity | protein dimerization activity | ubiquitin-like protein conjugating enzyme binding | metallochaperone activity | transition metal ion binding | enzyme regulator activity | steroid hormone receptor binding | protease binding | transcription coregulator activity | protein deglycase activity | oxidoreductase activity, acting on peroxide as acceptor | metal ion binding | heterocyclic compound binding | peptidase activity | oxidoreductase activity | cupric ion binding | RNA binding

GO Biological Process

positive regulation of immune response | maintenance of protein location in nucleus | negative regulation of phosphorylation | regulation of supramolecular fiber organization | regulation of hydrogen peroxide-induced cell death | negative regulation of intracellular transport | positive regulation of macromolecule biosynthetic process | L-dopa decarboxylase activator activity | regulation of cysteine-type endopeptidase activity | regulation of intracellular protein transport | regulation of cellular response to oxidative stress | positive regulation of cellular component organization | regulation of response to oxidative stress | regulation of cellular localization | positive regulation of lyase activity | positive regulation of ATP metabolic process | intracellular signal transduction | dopamine uptake involved in synaptic transmission | enzyme activator activity | positive regulation of apoptotic process | proteolysis | protein stabilization | regulation of localization | sulfur compound metabolic process | lactate biosynthetic process | positive regulation of DNA-binding transcription factor activity | regulation of programmed cell death | hormone secretion | negative regulation of cellular response to oxidative stress | peptidyl-amino acid modification | protein oxidation | cellular response to glyoxal | negative regulation of cysteine-type endopeptidase activity | glutathione metabolic process | establishment of localization | regulation of autophagy | regulation of immune system process | negative regulation of neuron death | negative regulation of cellular process | negative regulation of kinase activity | response to metal ion | positive regulation of signaling receptor activity | positive regulation of intrinsic apoptotic signaling pathway | defense response | response to drug | reactive oxygen species metabolic process | negative regulation of protein phosphorylation | glucose homeostasis | positive regulation of phosphate metabolic process | regulation of organelle organization | negative regulation of protein deubiquitination | cellular detoxification of aldehyde | response to antibiotic | dopamine transport | negative regulation of proteolysis | regulation of neuron death | positive regulation of oxidative phosphorylation | positive regulation of cellular biosynthetic process | cellular process | guanine deglycation | secretion | peptide hormone secretion | negative regulation of oxidative stress-induced neuron death | localization | regulation of removal of superoxide radicals | cellular detoxification | negative regulation of ubiquitin-dependent protein catabolic process | regulation of ubiquitin-protein transferase activity | protein transport | regulation of ubiquitin-specific protease activity | antioxidant activity | regulation of mitochondrial membrane potential | nucleotide metabolic process | negative regulation of signaling | chemical synaptic transmission | positive regulation of peptidyl-serine phosphorylation | positive regulation of reactive oxygen species metabolic process | positive regulation of androgen receptor activity | positive regulation of protein kinase activity | macromolecule localization | negative regulation of response to endoplasmic reticulum stress | negative regulation of apoptotic process | positive regulation of oxidoreductase activity | regulation of proteolysis | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | response to inorganic substance | regulation of protein export from nucleus | establishment of localization in cell | negative regulation of establishment of protein localization | negative regulation of cellular metabolic process | regulation of binding | regulation of oxidative phosphorylation | negative regulation of apoptotic signaling pathway | response to hydrogen peroxide | negative regulation of hydrogen peroxide-mediated programmed cell death | positive regulation of interleukin-8 production | regulation of protein kinase B signaling | negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway | regulation of immune response | regulation of cellular process | regulation of apoptotic process | regulation of oxidative phosphorylation uncoupler activity | regulation of metabolic process | guanine deglycation, methylglyoxal removal | negative regulation of ubiquitin-protein transferase activity | catabolic process | regulation of protein complex assembly | small GTPase mediated signal transduction | positive regulation of tyrosine 3-monooxygenase activity | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | negative regulation of oxidative stress-induced cell death | superoxide dismutase copper chaperone activity | cellular aromatic compound metabolic process | negative regulation of response to drug | cellular component organization | negative regulation of cellular protein catabolic process | positive regulation of protein binding | positive regulation of autophagy of mitochondrion | response to stimulus | positive regulation of dopamine biosynthetic process | positive regulation of NAD(P)H oxidase activity | regulation of mitochondrial ATP synthesis coupled electron transport | negative regulation of protein transport | methylglyoxal metabolic process | regulation of cellular protein localization | monocarboxylic acid metabolic process | cellular detoxification of methylglyoxal | positive regulation of immune system process | positive regulation of protein metabolic process | regulation of cellular protein catabolic process | negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway | negative regulation of intracellular protein transport | response to stress | positive regulation of cation transmembrane transport | regulation of intracellular steroid hormone receptor signaling pathway | negative regulation of protein kinase activity | regulation of response to endoplasmic reticulum stress | positive regulation of cellular protein localization | protein deglycosylation | regulation of response to drug | alcohol metabolic process | regulation of protein ubiquitination | protein localization to nucleus | protein deglycation, glyoxal removal | regulation of protein homodimerization activity | regulation of protein K48-linked deubiquitination | regulation of transcription regulatory region DNA binding | reproduction | cellular localization | secretion by cell | organic hydroxy compound transport | cellular nitrogen compound metabolic process | cellular response to toxic substance | maintenance of protein localization in organelle | regulation of dopamine metabolic process | negative regulation of transport | regulation of DNA binding | stress response to copper ion | regulation of protein transport | dopamine uptake | negative regulation of metabolic process | regulation of superoxide dismutase activity | positive regulation of RNA biosynthetic process | cofactor metabolic process | protein modification process | regulation of peptide transport | negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway | positive regulation of response to oxidative stress | cellular biosynthetic process | negative regulation of reactive oxygen species biosynthetic process | mitochondrion organization | macromolecule modification | cell-cell signaling | synaptic transmission, dopaminergic | activation of protein kinase activity | insulin secretion | regulation of intracellular transport | molecular function regulator | positive regulation of mitochondrion organization | DNA repair | regulation of catecholamine metabolic process | regulation of nucleic acid-templated transcription | regulation of membrane potential | regulation of cellular response to stress | regulation of neurotransmitter levels | positive regulation of monooxygenase activity | organic hydroxy compound metabolic process | negative regulation of neuron apoptotic process | peptidyl-lysine deglycation | positive regulation of reactive oxygen species biosynthetic process | regulation of superoxide metabolic process | regulation of proton transport | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | positive regulation of organelle organization | regulation of protein stability | negative regulation of phosphate metabolic process | cellular response to antibiotic | negative regulation of catalytic activity | antibiotic metabolic process | regulation of peptidase activity | phosphorus metabolic process | positive regulation of inflammatory response | regulation of oxidative stress-induced intrinsic apoptotic signaling pathway | membrane hyperpolarization | cellular response to DNA damage stimulus | negative regulation of proteasomal ubiquitin-dependent protein catabolic process | positive regulation of mitochondrial electron transport, NADH to ubiquinone | positive regulation of protein kinase B signaling | regulation of catalytic activity | protein deglycation, methylglyoxal removal | cellular response to oxidative stress | regulation of phosphorylation | regulation of intrinsic apoptotic signaling pathway | negative regulation of cellular protein localization | regulation of hormone levels | negative regulation of peptidase activity | regulation of protein deubiquitination | regulation of acute inflammatory response | regulation of gene expression | regulation of extrinsic apoptotic signaling pathway | regulation of cellular amino acid metabolic process | organic substance transport | response to ketone | cellular response to stress | synaptic signaling | stress response to metal ion | organophosphate metabolic process | negative regulation of hydrogen peroxide-induced cell death | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | positive regulation of cellular response to oxidative stress | positive regulation of dopamine metabolic process | adult locomotory behavior | positive regulation of ion transmembrane transport | regulation of protein localization to nucleus | regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway | response to mercury ion | regulation of nitrogen compound metabolic process | regulation of cysteine-type endopeptidase activity involved in apoptotic process | small molecule metabolic process | peptide transport | positive regulation of intracellular signal transduction | cellular amide metabolic process | negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway | regulation of transcription by RNA polymerase II | response to oxidative stress | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | protein localization to organelle | negative regulation of binding | glutathione deglycation | nucleobase-containing small molecule metabolic process | activation of protein kinase B activity | negative regulation of extrinsic apoptotic signaling pathway | peptidyl-cysteine deglycation | positive regulation of superoxide dismutase activity | positive regulation of cellular respiration | cellular ketone metabolic process | positive regulation of protein localization to nucleus | biosynthetic process | locomotory behavior | regulation of cellular protein metabolic process | positive regulation of acute inflammatory response to antigenic stimulus | fertilization | peroxiredoxin activity | response to toxic substance | negative regulation of protein export from nucleus | regulation of apoptotic signaling pathway | peptidyl-arginine deglycation | response to methylglyoxal | negative regulation of death-inducing signaling complex assembly | negative regulation of hydrogen peroxide-induced neuron death | regulation of protein sumoylation | phosphate-containing compound metabolic process | autophagy | cellular response to drug | regulation of mitochondrion organization | regulation of cellular response to drug | maintenance of protein location | peptide secretion | cell communication | negative regulation of protein binding | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of neuron apoptotic process | glyoxal metabolic process | positive regulation of transporter activity | inflammatory response | negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway | regulation of protein metabolic process | positive regulation of signal transduction | glycolate metabolic process | detoxification of copper ion | negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide | regulation of TRAIL receptor biosynthetic process | positive regulation of L-dopa biosynthetic process | regulation of androgen receptor signaling pathway | homeostatic process | regulation of protein phosphorylation | peptide metabolic process | positive regulation of oxidative stress-induced cell death | positive regulation of L-dopa decarboxylase activity | transcription coactivator activity | regulation of RNA metabolic process | negative regulation of protein ubiquitination | positive regulation of transport | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors | single fertilization | regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway | drug metabolic process | carboxylic acid metabolic process | regulation of autophagy of mitochondrion | positive regulation of molecular function | regulation of nucleocytoplasmic transport | regulation of proteasomal ubiquitin-dependent protein catabolic process | cellular aldehyde metabolic process | regulation of signaling receptor activity | protein metabolic process | regulation of establishment of protein localization | positive regulation of protein modification process | response to organic substance | regulation of cellular respiration | detoxification of mercury ion | tyrosine 3-monooxygenase activator activity | regulation of kinase activity | DNA metabolic process | import into cell | regulation of response to reactive oxygen species | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | metabolic process | negative regulation of response to oxidative stress | neurotransmitter uptake | regulation of receptor biosynthetic process | regulation of protein catabolic process | cellular oxidant detoxification | regulation of RNA biosynthetic process | oxidation-reduction process | negative regulation of programmed cell death | regulation of proteasomal protein catabolic process | negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway | positive regulation of inflammatory response to antigenic stimulus | cellular protein localization | amide transport | peptidyl-lysine modification | cellular response to hydrogen peroxide | chemical homeostasis | behavior | positive regulation of cell death | membrane depolarization | enzyme active site formation via L-cysteine sulfinic acid | hormone transport | nucleobase-containing compound metabolic process | cellular response to reactive oxygen species | negative regulation of protein complex assembly | organic substance metabolic process | response to copper ion | negative regulation of intrinsic apoptotic signaling pathway | positive regulation of acute inflammatory response | lactate metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | positive regulation of ion transport | response to reactive oxygen species | negative regulation of cellular protein metabolic process | positive regulation of programmed cell death | positive regulation of kinase activity | protein repair | maintenance of protein location in cell | regulation of ATP metabolic process | regulation of phosphate metabolic process | regulation of ion transmembrane transport | negative regulation of protein K48-linked deubiquitination | positive regulation of binding | glycolate biosynthetic process | positive regulation of autophagy | establishment of protein localization | positive regulation of cytokine production | positive regulation of pyrroline-5-carboxylate reductase activity | regulation of mitochondrial electron transport, NADH to ubiquinone | drug transport | regulation of reactive oxygen species biosynthetic process | regulation of peptidyl-serine phosphorylation | adult behavior | negative regulation of protein catabolic process | negative regulation of protein metabolic process | positive regulation of oxidative phosphorylation uncoupler activity | negative regulation of protein sumoylation | positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway | peptidyl-cysteine oxidation | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | regulation of extrinsic apoptotic signaling pathway via death domain receptors | signaling | regulation of transcription, DNA-templated | regulation of oxidoreductase activity | regulation of protein binding | positive regulation of intracellular steroid hormone receptor signaling pathway | guanine deglycation, glyoxal removal | positive regulation of DNA binding | regulation of transmembrane transporter activity | protein localization | organic acid metabolic process | positive regulation of phosphorylation | cellular protein metabolic process | enzyme regulator activity | regulation of cytokine production | regulation of endopeptidase activity | cation transport | cellular macromolecule localization | positive regulation of protein homodimerization activity | ammonium transport | regulation of cellular ketone metabolic process | regulation of ion transport | regulation of NAD(P)H oxidase activity | organelle organization | cellular protein modification process | monoamine transport | carbohydrate derivative metabolic process | regulation of transport | positive regulation of transcription, DNA-templated | regulation of reactive oxygen species metabolic process | detoxification | negative regulation of TRAIL-activated apoptotic signaling pathway | Ras protein signal transduction | neurotransmitter transport | positive regulation of nucleic acid-templated transcription | signal release | negative regulation of protein acetylation | transcription coregulator activity | positive regulation of transcription by RNA polymerase II | cellular modified amino acid metabolic process | heterocycle metabolic process | negative regulation of hydrolase activity | protein deglycase activity | oxidoreductase activity, acting on peroxide as acceptor | hydrogen peroxide metabolic process | regulation of generation of precursor metabolites and energy | positive regulation of metabolic process | cellular response to methylglyoxal | ion transport | cellular metabolic process | peptidase activity | cellular response to organic substance | regulation of protein localization | regulation of cell death | protein secretion | oxidoreductase activity | negative regulation of cell death | regulation of inflammatory response | carbohydrate homeostasis | glycoprotein metabolic process | regulation of ubiquitin-dependent protein catabolic process | negative regulation of proteolysis involved in cellular protein catabolic process | sexual reproduction | regulation of cellular component organization | positive regulation of apoptotic signaling pathway | negative regulation of reactive oxygen species metabolic process | positive regulation of signaling | signal transduction | regulation of signaling | negative regulation of endopeptidase activity | positive regulation of gene expression | positive regulation of transcription regulatory region DNA binding | negative regulation of ubiquitin-specific protease activity | macromolecule metabolic process | positive regulation of mitochondrial ATP synthesis coupled electron transport | maintenance of location in cell | multicellular organismal process | negative regulation of proteasomal protein catabolic process | regulation of phosphorus metabolic process

GO Cellular Component

mitochondrial matrix | mitochondrial intermembrane space | organelle inner membrane | chromosome | intracellular membrane-bounded organelle | synapse | catalytic complex | mitochondrial inner membrane | neuron projection | adherens junction | organelle membrane | cell body | cell | oxidoreductase complex | nuclear lumen | mitochondrial respiratory chain complex I | cytoplasm | respiratory chain complex I | intracellular organelle | endoplasmic reticulum | membrane microdomain | nuclear body | cell-cell adherens junction | presynapse | cell-cell junction | protein-containing complex | cell projection | PML body | endomembrane system | nucleoplasm | plasma membrane | chromatin | membrane raft | vesicle | mitochondrial respiratory chain | perinuclear region of cytoplasm | respiratory chain | extracellular exosome | mitochondrion | extracellular region | membrane-bounded organelle | extracellular vesicle | nucleus | organelle | mitochondrial envelope | extracellular space | cell periphery | axon | membrane-enclosed lumen | mitochondrial membrane | cytosol | intracellular | cell junction | membrane

PATHWAYS

PID_ALPHA_SYNUCLEIN_PATHWAY

PROTEIN FAMILY

DJ-1/PfpI | Protein/nucleic acid deglycase DJ-1 | Class I glutamine amidotransferase-like