QuickView for PRKD2;jsessionid=431B871A3A3298B30C5ED6893FF44F9D (gene)
- Gene Symbol:
- PRKD2
Homo sapiens - Full name:
- protein kinase D2
- Synonyms:
- HSPC187, PKD2, nPKC-D2, serine/threonine-protein kinase D2
- Genomic Location:
- Chr 19: 51869413-51912224
- Description:
-
The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral ...
- Orthologs:
- Mus musculus , Rattus norvegicus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
19q13.32
GO Molecular Function
kinase binding | cation binding | protein kinase binding | enzyme binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | protein kinase C activity | catalytic activity | ATP binding | protein kinase C binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | metal ion binding | heterocyclic compound binding | small molecule binding
GO Biological Process
positive regulation of immune response | regulation of ERK1 and ERK2 cascade | adaptive immune response | positive regulation of deacetylase activity | positive regulation of macromolecule biosynthetic process | positive regulation of locomotion | positive regulation of cellular component organization | immune response-regulating signaling pathway | intracellular signal transduction | regulation of localization | morphogenesis of an epithelium | positive regulation of DNA-binding transcription factor activity | peptidyl-amino acid modification | immune response-regulating cell surface receptor signaling pathway | regulation of immune system process | positive regulation of histone deacetylase activity | positive regulation of developmental process | immune response-activating cell surface receptor signaling pathway | positive regulation of epithelial cell proliferation | positive regulation of endothelial cell chemotaxis | T cell receptor signaling pathway | positive regulation of cell adhesion | positive regulation of phosphate metabolic process | regulation of organelle organization | positive regulation of endothelial cell proliferation | positive regulation of cellular component movement | positive regulation of vascular endothelial growth factor receptor signaling pathway | blood vessel morphogenesis | positive regulation of cellular biosynthetic process | cellular process | regulation of cell motility | epithelial tube morphogenesis | positive regulation of peptidyl-serine phosphorylation | regulation of vascular endothelial growth factor receptor signaling pathway | regulation of histone modification | regulation of chemotaxis | sphingolipid metabolic process | response to growth factor | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | regulation of T cell receptor signaling pathway | tissue development | regulation of angiogenesis | positive regulation of interleukin-8 production | regulation of immune response | regulation of cellular process | regulation of metabolic process | positive regulation of cellular protein metabolic process | epithelium development | cellular lipid metabolic process | positive regulation of epithelial cell migration | regulation of vasculature development | response to stimulus | peptidyl-threonine phosphorylation | positive regulation of antigen receptor-mediated signaling pathway | vasculature development | cellular response to vascular endothelial growth factor stimulus | positive regulation of immune system process | positive regulation of protein metabolic process | regulation of cell proliferation | tube morphogenesis | positive regulation of protein deacetylation | protein serine/threonine kinase activity | protein kinase C activity | sphingolipid biosynthetic process | regulation of histone deacetylase activity | cardiovascular system development | immune response-activating signal transduction | positive regulation of blood vessel endothelial cell migration | positive regulation of RNA biosynthetic process | protein modification process | regulation of cell adhesion | cellular biosynthetic process | macromolecule modification | blood vessel development | regulation of nucleic acid-templated transcription | system development | nitrogen compound metabolic process | regulation of signal transduction | positive regulation of organelle organization | endothelium development | multicellular organism development | regulation of MAPK cascade | phosphorus metabolic process | regulation of catalytic activity | lipid metabolic process | regulation of phosphorylation | positive regulation of chromosome organization | regulation of gene expression | positive regulation of chemotaxis | regulation of fibroblast growth factor receptor signaling pathway | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | vascular endothelial growth factor signaling pathway | protein autophosphorylation | regulation of nitrogen compound metabolic process | regulation of cell migration | enzyme linked receptor protein signaling pathway | positive regulation of intracellular signal transduction | regulation of cellular component movement | regulation of transcription by RNA polymerase II | positive regulation of hydrolase activity | regulation of endothelial cell migration | positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway | positive regulation of cell migration | biosynthetic process | regulation of cellular protein metabolic process | positive regulation of cell migration by vascular endothelial growth factor signaling pathway | angiogenesis | phosphorylation | lipid biosynthetic process | protein phosphorylation | positive regulation of fibroblast growth factor receptor signaling pathway | phosphate-containing compound metabolic process | positive regulation of histone deacetylation | cell communication | regulation of cellular metabolic process | regulation of protein deacetylation | positive regulation of DNA biosynthetic process | regulation of protein metabolic process | positive regulation of signal transduction | positive regulation of cell proliferation | regulation of protein phosphorylation | regulation of locomotion | regulation of RNA metabolic process | regulation of cellular response to growth factor stimulus | positive regulation of molecular function | activation of immune response | protein metabolic process | positive regulation of protein modification process | response to organic substance | tissue morphogenesis | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | endothelial tube morphogenesis | metabolic process | membrane lipid metabolic process | positive regulation of T cell receptor signaling pathway | regulation of RNA biosynthetic process | cell adhesion | immune response | protein kinase activity | organic substance metabolic process | cell death | positive regulation of histone modification | regulation of endothelial cell proliferation | positive regulation of NF-kappaB transcription factor activity | positive regulation of ERK1 and ERK2 cascade | regulation of phosphate metabolic process | regulation of chromosome organization | antigen receptor-mediated signaling pathway | positive regulation of cytokine production | positive regulation of endothelial cell migration | positive regulation of MAPK cascade | regulation of peptidyl-serine phosphorylation | anatomical structure formation involved in morphogenesis | regulation of epithelial cell migration | positive regulation of CREB transcription factor activity | regulation of cell communication | regulation of blood vessel endothelial cell migration | signaling | regulation of transcription, DNA-templated | regulation of epithelial cell proliferation | positive regulation of phosphorylation | cellular protein metabolic process | regulation of cytokine production | anatomical structure morphogenesis | regulation of developmental process | positive regulation of DNA metabolic process | protein kinase D signaling | kinase activity | developmental process | regulation of DNA biosynthetic process | peptidyl-serine phosphorylation | cellular protein modification process | vascular endothelial growth factor receptor signaling pathway | positive regulation of interleukin-2 production | tube development | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | regulation of histone deacetylation | transmembrane receptor protein tyrosine kinase signaling pathway | positive regulation of metabolic process | immune system process | cellular metabolic process | cellular response to organic substance | positive regulation of cell motility | circulatory system development | positive regulation of angiogenesis | regulation of cellular component organization | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | cellular response to growth factor stimulus | macromolecule metabolic process | multicellular organismal process | regulation of chromatin organization | regulation of phosphorus metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | Golgi apparatus | endomembrane system | nucleoplasm | plasma membrane | membrane-bounded organelle | nucleus | organelle | cell periphery | membrane-enclosed lumen | cytosol | intracellular | membrane
