QuickView for PTGR2 (gene)
- Gene Symbol:
- PTGR2
Homo sapiens - Full name:
- prostaglandin reductase 2
- Synonyms:
- HEL-S-298, PGR2, ZADH1, prostaglandin reductase 2, 15-oxoprostaglandin 13-reductase, 15-oxoprostaglandin-delta13-reductase, PRG-2, epididymis secretory protein Li 298, zinc binding alcohol dehydrogenase, domain containing 1, zinc-binding alcohol dehydrogenase domain-containing protein 1
- Genomic Location:
- Chr 14: 73388424-73421915
- Description:
-
This gene encodes an enzyme involved in the metabolism of prostaglandins. The encoded protein catalyzes the NADPH-dependent conversion of 15-keto-prostaglandin E2 to 15-keto-13,14-dihydro-prostaglandin E2. This protein may also be involved in regulating activation of the peroxisome proliferator-activated receptor. Alternative splicing results in mu...
- Orthologs:
- Mus musculus , Rattus norvegicus , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Gallus gallus , Canis lupus familiaris , Bos taurus , Danio rerio , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
14q24.3
GO Molecular Function
oxidoreductase activity, acting on CH-OH group of donors | cation binding | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor | catalytic activity | ion binding | zinc ion binding | 15-oxoprostaglandin 13-oxidase activity | transition metal ion binding | 13-prostaglandin reductase activity | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | metal ion binding | oxidoreductase activity, acting on the CH-CH group of donors | oxidoreductase activity
GO Biological Process
oxidoreductase activity, acting on CH-OH group of donors | cellular process | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor | cellular lipid metabolic process | monocarboxylic acid metabolic process | lipid metabolic process | small molecule metabolic process | carboxylic acid metabolic process | 15-oxoprostaglandin 13-oxidase activity | metabolic process | oxidation-reduction process | prostaglandin metabolic process | organic substance metabolic process | 13-prostaglandin reductase activity | fatty acid metabolic process | icosanoid metabolic process | organic acid metabolic process | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | oxidoreductase activity, acting on the CH-CH group of donors | cellular metabolic process | oxidoreductase activity
