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QuickView for Piwil2 (gene)


Gene Symbol:
PIWIL2 Homo sapiens Homo sapiens
Full name:
piwi like RNA-mediated gene silencing 2
Synonyms:
CT80, HILI, PIWIL1L, mili, piwi-like protein 2, 80kDa PIWIL2 short isoform, cancer/testis antigen 80, piwi-like 2, piwil2-like protein, testicular tissue protein Li 141
Genomic Location:
Chr 8: 22188796-22269545
Description:
PIWIL2 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells (Sasaki et al., 2003 [PubMed 12906857]).
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 8
8p21.3





GO Molecular Function

nuclease activity | cation binding | nucleic acid binding | mRNA binding | hydrolase activity | piRNA binding | ribonuclease activity | catalytic activity | hydrolase activity, acting on ester bonds | ion binding | organic cyclic compound binding | endoribonuclease activity | endonuclease activity | metal ion binding | heterocyclic compound binding | RNA binding

GO Biological Process

RNA metabolic process | gene silencing by RNA | regulation of cell cycle process | positive regulation of macromolecule biosynthetic process | RNA processing | positive regulation of cellular component organization | developmental process involved in reproduction | nuclease activity | regulation of meiotic cell cycle | positive regulation of meiosis I | DNA modification | negative regulation of cellular process | regulation of histone H3-K14 acetylation | cell differentiation | male gamete generation | regulation of organelle organization | positive regulation of cellular biosynthetic process | cellular process | regulation of transposition | multicellular organismal reproductive process | stem cell population maintenance | regulation of histone modification | regulation of cell cycle | positive regulation of nitrogen compound metabolic process | regulation of histone H3-K9 acetylation | gamete generation | regulation of cellular process | gene silencing | regulation of metabolic process | organic cyclic compound metabolic process | positive regulation of translation | positive regulation of cellular protein metabolic process | cellular aromatic compound metabolic process | regulation of meiosis I | female gamete generation | positive regulation of protein metabolic process | germ cell development | posttranscriptional regulation of gene expression | reproduction | cellular nitrogen compound metabolic process | nucleic acid phosphodiester bond hydrolysis | positive regulation of meiotic cell cycle | negative regulation of metabolic process | ribonuclease activity | macromolecule modification | nitrogen compound metabolic process | reproductive process | positive regulation of organelle organization | multicellular organism development | negative regulation of transposition | positive regulation of chromosome organization | piRNA biosynthetic process | positive regulation of cell cycle | regulation of gene expression | methylation | cell cycle | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | DNA methylation | oogenesis | piRNA metabolic process | positive regulation of histone H3-K9 acetylation | regulation of cellular protein metabolic process | RNA 5'-end processing | regulation of cellular metabolic process | regulation of protein metabolic process | positive regulation of protein acetylation | positive regulation of meiotic nuclear division | endoribonuclease activity | multicellular organism reproduction | positive regulation of protein modification process | regulation of meiotic nuclear division | DNA metabolic process | positive regulation of peptidyl-lysine acetylation | anatomical structure development | metabolic process | positive regulation of histone H3-K14 acetylation | RNA phosphodiester bond hydrolysis, endonucleolytic | nucleobase-containing compound metabolic process | organic substance metabolic process | maintenance of cell number | negative regulation of gene expression | positive regulation of histone modification | RNA phosphodiester bond hydrolysis | gene expression | endonuclease activity | regulation of chromosome organization | meiotic cell cycle | cell development | developmental process | positive regulation of cell cycle process | spermatogenesis | DNA methylation involved in gamete generation | regulation of histone acetylation | positive regulation of histone acetylation | germ-line stem cell population maintenance | ncRNA metabolic process | heterocycle metabolic process | positive regulation of metabolic process | cellular metabolic process | regulation of translation | sexual reproduction | regulation of cellular component organization | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process | regulation of chromatin organization

GO Cellular Component

pole plasm | PET complex | chromosome | intracellular membrane-bounded organelle | polysome | cell | ribonucleoprotein granule | cytoplasm | perinucleolar chromocenter | P granule | intracellular organelle | germ plasm | chromocenter | protein-containing complex | ribonucleoprotein complex | membrane-bounded organelle | dense body | nucleus | organelle | cytoplasmic ribonucleoprotein granule | chromatoid body | intracellular | pi-body