QuickView for RABGGTB (gene)
- Gene Symbol:
- RABGGTB
Homo sapiens - Full name:
- Rab geranylgeranyltransferase beta subunit
- Synonyms:
- GGTB, geranylgeranyl transferase type-2 subunit beta, GGTase-II-beta, rab GG transferase beta, rab GGTase beta, type II protein geranyl-geranyltransferase subunit beta
- Genomic Location:
- Chr 1: 76024474-76033352
- Description:
-
This gene encodes the beta-subunit of the enzyme Rab geranylgeranyl-transferase (RabGGTase), which belongs to the protein prenyltransferase family. RabGGTase catalyzes the post-translational addition of geranylgeranyl groups to C-terminal cysteine residues of Rab GTPases. Three small nucleolar RNA genes are present in the intronic regions of this g...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Danio rerio , Gallus gallus , Bos taurus , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
1p31.1
GO Molecular Function
protein geranylgeranyltransferase activity | GTPase binding | cation binding | enzyme binding | transferase activity, transferring alkyl or aryl (other than methyl) groups | prenyltransferase activity | Ras GTPase binding | catalytic activity | protein prenyltransferase activity | ion binding | Rab geranylgeranyltransferase activity | protein binding | zinc ion binding | transferase activity | transition metal ion binding | small GTPase binding | Rab GTPase binding | metal ion binding
GO Biological Process
regulation of programmed cell death | cellular process | regulation of cellular process | regulation of apoptotic process | protein prenylation | protein modification process | macromolecule modification | nitrogen compound metabolic process | nervous system process | protein metabolic process | metabolic process | visual perception | organic substance metabolic process | sensory perception of light stimulus | sensory perception | cellular protein metabolic process | cellular protein modification process | cellular metabolic process | regulation of cell death | protein geranylgeranylation | post-translational protein modification | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
catalytic complex | cell | Rab-protein geranylgeranyltransferase complex | cytoplasm | protein-containing complex | plasma membrane | transferase complex | cell periphery | cytosol | intracellular | membrane
