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QuickView for Rab4a (gene)


Gene Symbol:
RAB4A Homo sapiens Homo sapiens
Full name:
RAB4A, member RAS oncogene family
Synonyms:
HRES-1, HRES-1/RAB4, HRES1, RAB4, ras-related protein Rab-4A, HTLV-1 related endogenous sequence
Genomic Location:
Chr 1: 227473502-227507141
Description:
This gene is a member of the largest group in the Ras superfamily of small GTPases, which regulate membrane trafficking. The encoded protein is associated with early endosomes and is involved in their sorting and recycling. The protein also plays a role in regulating the recycling of receptors from endosomes to the plasma membrane. Alternatively sp...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Cytogenetic Map:
chr 1
1q42.13





GO Molecular Function

enzyme activator activity | GDP binding | guanyl ribonucleotide binding | ribonucleoside binding | enzyme binding | ribonucleotide binding | syntaxin binding | nucleotide binding | protein transporter activity | signaling receptor binding | hydrolase activity | carbohydrate derivative binding | pyrophosphatase activity | molecular function regulator | catalytic activity | anion binding | ATPase binding | nucleoside-triphosphatase activity | purine nucleotide binding | transporter activity | ion binding | organic cyclic compound binding | GTPase activity | purine nucleoside binding | purine ribonucleoside triphosphate binding | protein binding | ATPase activator activity | GTP binding | hydrolase activity, acting on acid anhydrides | nucleoside binding | SNARE binding | purine ribonucleotide binding | enzyme regulator activity | ATPase regulator activity | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | guanyl nucleotide binding | glutamate receptor binding | ionotropic glutamate receptor binding | small molecule binding

GO Biological Process

positive regulation of ATPase activity | antigen processing and presentation | intracellular signal transduction | enzyme activator activity | regulation of localization | phosphatidylinositol metabolic process | establishment of localization | phospholipid metabolic process | intracellular transport | cellular process | localization | protein transport | macromolecule localization | positive regulation of catalytic activity | establishment of localization in cell | regulation of cellular process | small GTPase mediated signal transduction | cellular lipid metabolic process | protein transporter activity | response to stimulus | regulation of ATPase activity | intracellular protein transport | cellular localization | cellular biosynthetic process | molecular function regulator | phosphorus metabolic process | regulation of catalytic activity | lipid metabolic process | organic substance transport | organophosphate metabolic process | phospholipid biosynthetic process | peptide transport | positive regulation of hydrolase activity | biosynthetic process | lipid biosynthetic process | phosphate-containing compound metabolic process | cell communication | glycerolipid metabolic process | positive regulation of molecular function | ATPase activator activity | glycerophospholipid biosynthetic process | metabolic process | Rab protein signal transduction | cellular protein localization | amide transport | regulation of vesicle-mediated transport | organic substance metabolic process | phosphatidylinositol biosynthetic process | establishment of protein localization | signaling | regulation of endocytosis | protein localization | enzyme regulator activity | cellular macromolecule localization | glycerophospholipid metabolic process | regulation of transport | ATPase regulator activity | Ras protein signal transduction | immune system process | cellular metabolic process | regulation of cellular component organization | signal transduction

GO Cellular Component

intracellular membrane-bounded organelle | postsynaptic endosome | early endosome membrane | synapse | organelle membrane | cytoplasmic vesicle | cell | cytoplasm | intracellular organelle | endosome membrane | postsynaptic recycling endosome | recycling endosome | endomembrane system | postsynapse | plasma membrane | vesicle | perinuclear region of cytoplasm | extracellular exosome | endosome | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | recycling endosome membrane | vesicle membrane | extracellular space | cell periphery | early endosome | cytosol | intracellular vesicle | intracellular | membrane | cytoplasmic vesicle membrane