QuickView for Rap1b (gene)

Gene Symbol:

RAP1B Homo sapiens

Full name:

RAP1B, member of RAS oncogene family

Synonyms:

K-REV, RAL1B, ras-related protein Rap-1b, GTP-binding protein smg p21B, RAS-related protein RAP1B, Ras family small GTP binding protein RAP1B, small GTP binding protein

Genomic Location:

Chr 12: 67290919-67340641

Description:

This gene encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. This protein also plays a role in regulati...

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This gene encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. This protein also plays a role in regulating outside-in signaling in platelets. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 5, 6 and 9.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Danio rerio ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CACTGTG_MIR128A_MIR128B ,  TTTGCAC_MIR19A_MIR19B ,  TGAATGT_MIR181A_MIR181B_MIR181C_MIR181D ,  GATA_Q6 ,  AGCGCTT_MIR518F_MIR518E_MIR518A ,  TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P ,  GTACTGT_MIR101 ,  GATAAGR_GATA_C ,  GTGCAAT_MIR25_MIR32_MIR92_MIR363_MIR367 ,  CTTTGTA_MIR524 ,  TGTATGA_MIR4853P ,  TTGGAGA_MIR5155P_MIR519E ,  P53_02 ,  AGCTCCT_MIR28 ,  ATGTTAA_MIR302C ,  ATGTTTC_MIR494 ,  LMO2COM_02 ,  TCCAGAT_MIR5165P ,  GCGCTTT_MIR518B_MIR518C_MIR518D ,  TTGTTT_FOXO4_01 ,  CAGTATT_MIR200B_MIR200C_MIR429 ,  GAGCCAG_MIR149 ,  CTGAGCC_MIR24 ,  CTTTGT_LEF1_Q2 ,  AACTTT_UNKNOWN ,  AAGTCCA_MIR422B_MIR422A

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-1 ,  Predicted Gene Targets for miR-101 ,  Predicted Gene Targets for miR-128 ,  Predicted Gene Targets for miR-139 ,  Predicted Gene Targets for miR-144 ,  Predicted Gene Targets for miR-181 ,  Predicted Gene Targets for miR-19 ,  Predicted Gene Targets for miR-194 ,  Predicted Gene Targets for miR-200b ,  Predicted Gene Targets for miR-217 ,  Predicted Gene Targets for miR-23 ,  Predicted Gene Targets for miR-24 ,  Predicted Gene Targets for miR-25 ,  Predicted Gene Targets for miR-28 ,  Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-329 ,  Predicted Gene Targets for miR-330 ,  Predicted Gene Targets for miR-339 ,  Predicted Gene Targets for miR-378* ,  Predicted Gene Targets for miR-381 ,  Predicted Gene Targets for miR-494 ,  Predicted Gene Targets for miR-9 ,  Predicted Gene Targets for miR-124u ,  Predicted Gene Targets for miR-149 ,  Predicted Gene Targets for miR-31 ,  Predicted Gene Targets for miR-485-3p ,  Predicted Gene Targets for miR-495 ,  Predicted Gene Targets for miR-496 ,  Predicted Gene Targets for miR-500

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Cytogenetic Map:

12q15

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