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QuickView for Resveratrol (compound)

Name: resveratrol
PubChem Compound ID: 1548910
Molecular formula: C14H12O3
Molecular weight: 228.243 g/mol
5-[(1Z)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol; NCGC00024003-02; CAS-501-36-0; Lopac-R-5010; TNP00294; 5-[(Z)-2-(4-hydroxyphenyl)vinyl]benzene-1,3-diol; NCGC00017352-01; cis-resveratrol; CHEBI:36002; NCGC00015894-02.
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Name: resveratrol
Name (isomeric): DB02709
Drug Type: small molecule
3,4',5-Stilbenetriol; trans-3,4',5-trihydroxystilbene; (E)-resveratrol; (E)-5-[2-(4-hydroxyphenyl)ethenyl]-1,3-benzendiol; (E)-5-[2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol; 3,4',5-trihydroxy-stilbene; (E)-5-(2-(4-hydroxyphenyl)ethenyl)-1,3-benzenediol; (E)-5-(p-Hydroxystyryl)resorcinol; 3,4',5-Trihydroxystilbene
Category: Anticarcinogenic Agents, Antioxidants, Antimutagenic Agents, Enzyme Inhibitors, Platelet Aggregation Inhibitors, Antineoplastic Agents, Phytogenic
CAS number: 501-36-0
Indication: Being investigated for the treatment of Herpes labialis infections (cold sores).
Resveratrol, a phytoalexin, has been found to inhibit herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) replication in a dose-dependent, reversible manner, although this is only one of its many pharmaceutical properties. In some countries where there is higher consumption of red wine, there appears to be a lower incidence of heart disease. Other...
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Mechanism of Action: Resveratrol suppresses NF-kappaB (NF-kappaB) activation in HSV infected cells. Reports have indicated that HSV activates NF-kappaB during productive infection and this may be an essential aspect of its replication scheme [PMID: 9705914].
Absorption: High absorption but very low bioavailability.
Protein binding: Strong affinity towards protein binding.
Biotransformation: Hepatic. Rapidly metabolized and excreted.
Affected organisms: Humans and other mammals