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QuickView for Resveratrol (compound)
PubChem
| Name: | resveratrol |
|---|---|
| PubChem Compound ID: | 1548910 |
| Molecular formula: | C14H12O3 |
| Molecular weight: | 228.243 g/mol |
| Synonyms: |
5-[(1Z)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol; NCGC00024003-02; CAS-501-36-0; Lopac-R-5010; TNP00294; 5-[(Z)-2-(4-hydroxyphenyl)vinyl]benzene-1,3-diol; NCGC00017352-01; cis-resveratrol; CHEBI:36002; NCGC00015894-02.
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DrugBank
Identification
| Name: | resveratrol |
|---|---|
| Name (isomeric): | DB02709 |
| Drug Type: | small molecule |
| Synonyms: |
3,4',5-Stilbenetriol; trans-3,4',5-trihydroxystilbene; (E)-resveratrol; (E)-5-[2-(4-hydroxyphenyl)ethenyl]-1,3-benzendiol; (E)-5-[2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol; 3,4',5-trihydroxy-stilbene; (E)-5-(2-(4-hydroxyphenyl)ethenyl)-1,3-benzenediol; (E)-5-(p-Hydroxystyryl)resorcinol; 3,4',5-Trihydroxystilbene
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| Category: | Anticarcinogenic Agents, Antioxidants, Antimutagenic Agents, Enzyme Inhibitors, Platelet Aggregation Inhibitors, Antineoplastic Agents, Phytogenic |
| CAS number: | 501-36-0 |
Pharmacology
| Indication: | Being investigated for the treatment of Herpes labialis infections (cold sores). |
|---|---|
| Pharmacology: |
Resveratrol, a phytoalexin, has been found to inhibit herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) replication in a dose-dependent, reversible manner, although this is only one of its many pharmaceutical properties. In some countries where there is higher consumption of red wine, there appears to be a lower incidence of heart disease. Other...
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| Mechanism of Action: | Resveratrol suppresses NF-kappaB (NF-kappaB) activation in HSV infected cells. Reports have indicated that HSV activates NF-kappaB during productive infection and this may be an essential aspect of its replication scheme [PMID: 9705914]. |
| Absorption: | High absorption but very low bioavailability. |
| Protein binding: | Strong affinity towards protein binding. |
| Biotransformation: | Hepatic. Rapidly metabolized and excreted. |
| Affected organisms: | Humans and other mammals |
Targets
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