QuickView for Roc1 (gene)
- Gene Symbol:
- Roc1a
D. melanogaster - Full name:
- CG16982 gene product from transcript CG16982-RB
- Synonyms:
- anon-EST:Posey65, BEST:CK01110, CG16982, CK01110, DmelCG16982, Dmel_CG16982, dRbx1, dRoc1a, EG:115C2.11, Rbx1, Rbx1/Roc, ROC1, Roc1a, Roc1alpha
- Genomic Location:
- Chr X: 541320-542636
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , C. elegans , Macaca mulatta , Gallus gallus , Danio rerio , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
HEN1_02 , IK3_01 , CDPCR3HD_01 , TGIF_01 , MEIS1_01 , CTTTAAR_UNKNOWN , SREBP1_Q6 , GR_Q6_01 , GR_01 , GTGTCAA_MIR514
GO Molecular Function
NEDD8 transferase activity | cation binding | catalytic activity | ubiquitin-like protein transferase activity | ubiquitin protein ligase activity | ion binding | protein binding | zinc ion binding | cullin family protein binding | ubiquitin-protein transferase activity | transferase activity | transition metal ion binding | ubiquitin-like protein ligase activity | metal ion binding
GO Biological Process
negative regulation of cellular response to insulin stimulus | regulation of neurogenesis | positive regulation of neuron remodeling | proteolysis | regulation of cell development | lipid storage | negative regulation of cellular process | positive regulation of developmental process | cell differentiation | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | nervous system development | positive regulation of protein catabolic process | neurogenesis | generation of neurons | cellular process | organic substance catabolic process | localization | proteolysis involved in cellular protein catabolic process | positive regulation of neuron maturation | negative regulation of signaling | macromolecule localization | regulation of proteolysis | positive regulation of nitrogen compound metabolic process | regulation of canonical Wnt signaling pathway | regulation of cell differentiation | regulation of cellular process | regulation of metabolic process | catabolic process | regulation of cell maturation | positive regulation of cellular protein metabolic process | positive regulation of cellular protein catabolic process | response to stimulus | positive regulation of protein metabolic process | regulation of cellular protein catabolic process | protein neddylation | positive regulation of proteolysis involved in cellular protein catabolic process | cellular protein catabolic process | positive regulation of proteolysis | proteasomal protein catabolic process | protein modification process | macromolecule modification | system development | nitrogen compound metabolic process | regulation of signal transduction | multicellular organism development | regulation of neuron maturation | regulation of neuron differentiation | protein catabolic process | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | protein modification by small protein conjugation | negative regulation of insulin receptor signaling pathway | ubiquitin protein ligase activity | positive regulation of cell differentiation | cell proliferation | regulation of cellular protein metabolic process | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | positive regulation of proteasomal protein catabolic process | positive regulation of cell maturation | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | proteasome-mediated ubiquitin-dependent protein catabolic process | regulation of proteasomal ubiquitin-dependent protein catabolic process | protein metabolic process | protein ubiquitination | cellular macromolecule catabolic process | anatomical structure development | cell surface receptor signaling pathway | positive regulation of neurogenesis | metabolic process | lipid localization | positive regulation of cell development | positive regulation of ubiquitin-dependent protein catabolic process | ubiquitin-protein transferase activity | regulation of protein catabolic process | regulation of proteasomal protein catabolic process | organic substance metabolic process | regulation of insulin receptor signaling pathway | protein modification by small protein conjugation or removal | regulation of cellular response to insulin stimulus | regulation of Wnt signaling pathway | ubiquitin-dependent protein catabolic process | smoothened signaling pathway | regulation of neuron remodeling | organonitrogen compound catabolic process | regulation of cell communication | negative regulation of signal transduction | signaling | cellular protein metabolic process | regulation of nervous system development | regulation of developmental process | developmental process | negative regulation of canonical Wnt signaling pathway | cellular protein modification process | positive regulation of metabolic process | negative regulation of Wnt signaling pathway | positive regulation of neuron differentiation | cellular metabolic process | modification-dependent protein catabolic process | regulation of ubiquitin-dependent protein catabolic process | signal transduction | regulation of signaling | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
Cul2-RING ubiquitin ligase complex | intracellular membrane-bounded organelle | catalytic complex | nuclear ubiquitin ligase complex | cell | Cul3-RING ubiquitin ligase complex | intracellular organelle | ubiquitin ligase complex | protein-containing complex | nuclear SCF ubiquitin ligase complex | Cul7-RING ubiquitin ligase complex | transferase complex | cullin-RING ubiquitin ligase complex | membrane-bounded organelle | nucleus | organelle | SCF ubiquitin ligase complex | Cul4-RING E3 ubiquitin ligase complex | intracellular
