QuickView for SGK3;jsessionid=6B1ABBEFB65E9E9C6B12E5A3C53E33BC (gene)
- Gene Symbol:
- SGK3
Homo sapiens - Full name:
- serum/glucocorticoid regulated kinase family member 3
- Synonyms:
- CISK, SGK2, SGKL, serine/threonine-protein kinase Sgk3, cytokine-independent survival kinase
- Genomic Location:
- Chr 8: 67787445-67936811
- Description:
-
This gene is a member of the Ser/Thr protein kinase family and encodes a phosphoprotein with a PX (phox homology) domain. The protein phosphorylates several target proteins and has a role in neutral amino acid transport and activation of potassium and chloride channels. Alternate transcriptional splice variants, encoding different isoforms, have be...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Schizosaccharomyces pombe , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: miRecords):
- Cytogenetic Map:
-
8q13.1
GO Molecular Function
channel regulator activity | ribonucleotide binding | sodium channel regulator activity | lipid binding | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | phospholipid binding | chloride channel regulator activity | molecular function regulator | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | potassium channel regulator activity | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | calcium channel regulator activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | phosphatidylinositol binding | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | heterocyclic compound binding | small molecule binding
GO Biological Process
regulation of extrinsic apoptotic signaling pathway in absence of ligand | intracellular signal transduction | regulation of localization | regulation of programmed cell death | peptidyl-amino acid modification | establishment of localization | negative regulation of cellular process | cellular process | channel regulator activity | regulation of cell motility | localization | negative regulation of signaling | negative regulation of apoptotic process | negative regulation of apoptotic signaling pathway | regulation of cellular process | sodium channel regulator activity | regulation of apoptotic process | regulation of metabolic process | response to stimulus | regulation of cell proliferation | protein serine/threonine kinase activity | chloride channel regulator activity | protein modification process | macromolecule modification | molecular function regulator | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | regulation of signal transduction | phosphorus metabolic process | ion transmembrane transport | regulation of gene expression | regulation of extrinsic apoptotic signaling pathway | regulation of nitrogen compound metabolic process | regulation of cell migration | regulation of cellular component movement | negative regulation of extrinsic apoptotic signaling pathway | phosphorylation | potassium channel regulator activity | regulation of apoptotic signaling pathway | protein phosphorylation | phosphate-containing compound metabolic process | cell communication | regulation of cellular metabolic process | negative regulation of extrinsic apoptotic signaling pathway in absence of ligand | regulation of locomotion | regulation of RNA metabolic process | calcium channel regulator activity | protein metabolic process | regulation of growth | regulation of DNA-binding transcription factor activity | metabolic process | regulation of RNA biosynthetic process | negative regulation of programmed cell death | protein kinase activity | organic substance metabolic process | regulation of cell communication | negative regulation of signal transduction | transmembrane transport | signaling | regulation of transcription, DNA-templated | cellular protein metabolic process | kinase activity | regulation of cell growth | peptidyl-serine phosphorylation | cellular protein modification process | ion transport | cellular metabolic process | regulation of cell death | negative regulation of cell death | regulation of cellular component organization | signal transduction | regulation of signaling | macromolecule metabolic process
GO Cellular Component
cytoplasmic vesicle | cell | cytoplasm | intracellular organelle | recycling endosome | endomembrane system | vesicle | endosome | membrane-bounded organelle | organelle | early endosome | cytosol | intracellular vesicle | intracellular
