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QuickView for SNX33;jsessionid=AA6628D14A25F6F3F0B225CBB483AD40 (gene)


Gene Symbol:
SNX33 Homo sapiens Homo sapiens
Full name:
sorting nexin 33
Synonyms:
SH3PX3, SH3PXD3C, SNX30, sorting nexin-33, SH3 and PX domain containing 3, SH3 and PX domain-containing protein 3
Genomic Location:
Chr 15: 73728403-73738023
Description:
The protein encoded by this gene is involved in cytoskeletal reorganization, vesicle trafficking, endocytosis, and mitosis. The encoded protein is essential for the creation of the cleavage furrow during mitosis and for completion of mitosis. Two transcript variants encoding different isoforms have been found for this gene.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 15
15q24.2


Transcripts Names
NM_153271
NM_001318146
Protein Names
B1NM17
Q8WV41



GO Molecular Function

lipid binding | phospholipid binding | anion binding | identical protein binding | ion binding | protein binding | phosphatidylinositol binding

GO Biological Process

mitotic cytokinesis | regulation of cellular localization | regulation of localization | establishment of localization | negative regulation of cellular process | positive regulation of protein catabolic process | membrane organization | intracellular transport | cellular process | localization | cytokinetic process | protein transport | cytoskeleton-dependent cytokinesis | macromolecule localization | endomembrane system organization | regulation of proteolysis | positive regulation of nitrogen compound metabolic process | establishment of localization in cell | regulation of cellular process | regulation of metabolic process | positive regulation of cellular protein metabolic process | cellular component organization | regulation of cellular protein localization | positive regulation of protein metabolic process | endosomal transport | intracellular protein transport | positive regulation of cellular protein localization | positive regulation of membrane protein ectodomain proteolysis | cellular localization | positive regulation of proteolysis | negative regulation of transport | macropinocytosis | cleavage furrow formation | regulation of protein localization to cell surface | negative regulation of cellular protein localization | pinocytosis | plasma membrane organization | positive regulation of protein localization to cell surface | organic substance transport | cell cycle | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | peptide transport | vesicle-mediated transport | cell division | regulation of cellular protein metabolic process | cytokinesis | protein import | regulation of cellular metabolic process | regulation of protein metabolic process | import into cell | mitotic cell cycle | negative regulation of endocytosis | regulation of protein catabolic process | cellular protein localization | membrane invagination | amide transport | regulation of vesicle-mediated transport | endocytosis | establishment of protein localization | vesicle organization | regulation of endocytosis | protein localization | cellular macromolecule localization | endosome organization | organelle organization | negative regulation of protein localization to cell surface | regulation of transport | positive regulation of metabolic process | plasma membrane tubulation | regulation of protein localization | regulation of cellular component organization

GO Cellular Component

extrinsic component of membrane | organelle membrane | cytoplasmic vesicle | cell | cytoplasm | intracellular organelle | vesicle | membrane-bounded organelle | organelle | vesicle membrane | cytosol | intracellular vesicle | intracellular | membrane | cytoplasmic vesicle membrane