QuickView for Sfrp2 (gene)

GO Molecular Function

enzyme activator activity | transmembrane signaling receptor activity | protein-containing complex binding | peptidase activator activity | signaling receptor binding | molecular function regulator | signaling receptor activity | integrin binding | cell adhesion molecule binding | protein binding | receptor regulator activity | receptor ligand activity | Wnt-activated receptor activity | enzyme regulator activity | Wnt-protein binding | endopeptidase activator activity | fibronectin binding

GO Biological Process

regulation of JUN kinase activity | response to extracellular stimulus | negative regulation of JNK cascade | negative regulation of phosphorylation | limb development | response to radiation | cellular response to X-ray | positive regulation of macromolecule biosynthetic process | regulation of cysteine-type endopeptidase activity | response to nutrient levels | negative regulation of MAPK cascade | negative regulation of embryonic development | extracellular structure organization | regulation of neurogenesis | chondrocyte development | developmental process involved in reproduction | enzyme activator activity | positive regulation of apoptotic process | regulation of cell development | regulation of localization | morphogenesis of an epithelium | gonad development | regulation of programmed cell death | response to X-ray | negative regulation of cysteine-type endopeptidase activity | negative regulation of BMP signaling pathway | negative regulation of cellular process | negative regulation of kinase activity | negative regulation of mesoderm development | positive regulation of developmental process | regulation of MAP kinase activity | negative regulation of RNA biosynthetic process | embryonic appendage morphogenesis | bone development | regulation of cardiac muscle cell apoptotic process | cell differentiation | nervous system development | cellular response to extracellular stimulus | response to drug | negative regulation of protein phosphorylation | neurogenesis | positive regulation of cell adhesion | positive regulation of phosphate metabolic process | convergent extension | generation of neurons | mesenchyme development | negative regulation of proteolysis | blood vessel morphogenesis | pattern specification process | negative regulation of stress-activated protein kinase signaling cascade | positive regulation of cellular biosynthetic process | cellular process | regulation of cell motility | negative regulation of planar cell polarity pathway involved in axis elongation | epithelial tube morphogenesis | limb morphogenesis | heart morphogenesis | negative regulation of signaling | developmental growth | regulation of dopaminergic neuron differentiation | positive regulation of peptidyl-serine phosphorylation | negative regulation of developmental growth | reproductive system development | canonical Wnt signaling pathway | regulation of embryonic development | immune system development | negative regulation of mesodermal cell fate specification | negative regulation of nucleic acid-templated transcription | negative regulation of apoptotic process | digestive tract morphogenesis | regulation of proteolysis | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | negative regulation of cell migration | regulation of neuron projection development | regulation of canonical Wnt signaling pathway | negative regulation of cellular metabolic process | tissue development | regulation of fat cell differentiation | regulation of cell differentiation | negative regulation of apoptotic signaling pathway | negative regulation of cell motility | regulation of angiogenesis | regulation of cellular process | positive regulation of cell growth | regulation of osteoblast differentiation | regulation of apoptotic process | regulation of metabolic process | peptidase activator activity | positive regulation of cellular protein metabolic process | positive regulation of cell adhesion mediated by integrin | epithelium development | regulation of establishment of planar polarity | cellular component organization | regulation of cell division | development of primary sexual characteristics | regulation of mesodermal cell fate specification | branching involved in blood vessel morphogenesis | regulation of vasculature development | response to stimulus | vasculature development | negative regulation of epithelial to mesenchymal transition | embryonic limb morphogenesis | regulation of peptidyl-tyrosine phosphorylation | embryonic epithelial tube formation | positive regulation of protein metabolic process | positive regulation of peptidase activity | negative regulation of protein kinase activity | regulation of cell proliferation | tube morphogenesis | negative regulation of non-canonical Wnt signaling pathway | programmed cell death | supramolecular fiber organization | epithelial tube formation | reproduction | negative regulation of dermatome development | cardiovascular system development | cardiac ventricle morphogenesis | positive regulation of proteolysis | axis elongation | extracellular matrix organization | G-protein coupled receptor signaling pathway | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | hemopoiesis | cartilage development | regulation of cell adhesion | Wnt signaling pathway, planar cell polarity pathway | embryo development | negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway | cell-cell signaling | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage | molecular function regulator | cell surface receptor signaling pathway involved in cell-cell signaling | blood vessel development | anterior/posterior pattern specification | regulation of nucleic acid-templated transcription | regulation of cellular response to stress | apoptotic process | system development | chondrocyte differentiation | reproductive process | regulation of signal transduction | Wnt signaling pathway | negative regulation of growth | negative regulation of phosphate metabolic process | multicellular organism development | negative regulation of catalytic activity | regulation of peptidase activity | regulation of MAPK cascade | regulation of BMP signaling pathway | negative regulation of striated muscle cell apoptotic process | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | regulation of intrinsic apoptotic signaling pathway | regulation of ossification | negative regulation of peptidase activity | regulation of neuron differentiation | regulation of gene expression | stem cell proliferation | regulation of extrinsic apoptotic signaling pathway | regulation of cell fate specification | neural tube closure | outflow tract morphogenesis | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | cellular response to radiation | animal organ morphogenesis | regulation of nitrogen compound metabolic process | regulation of cell migration | regulation of cysteine-type endopeptidase activity involved in apoptotic process | negative regulation of cellular response to growth factor stimulus | neural tube formation | negative regulation of protein serine/threonine kinase activity | regulation of cellular component movement | regulation of transcription by RNA polymerase II | response to nutrient | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | positive regulation of hydrolase activity | positive regulation of cell differentiation | negative regulation of extrinsic apoptotic signaling pathway | non-canonical Wnt signaling pathway | negative regulation of cardiac muscle cell apoptotic process | cell proliferation | neural tube development | regulation of cellular protein metabolic process | positive regulation of ossification | angiogenesis | regulation of cell adhesion mediated by integrin | digestive tract development | positive regulation of endopeptidase activity | convergent extension involved in axis elongation | negative regulation of stress-activated MAPK cascade | regulation of apoptotic signaling pathway | regulation of muscle cell apoptotic process | chordate embryonic development | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | hematopoietic stem cell proliferation | skeletal system morphogenesis | regulation of protein metabolic process | positive regulation of signal transduction | heart development | positive regulation of cell proliferation | regulation of protein phosphorylation | bone morphogenesis | regulation of locomotion | embryo development ending in birth or egg hatching | negative regulation of MAP kinase activity | regulation of RNA metabolic process | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors | negative regulation of cell growth | regulation of cellular response to growth factor stimulus | negative regulation of cell fate commitment | embryonic morphogenesis | positive regulation of molecular function | negative regulation of cell fate specification | positive regulation of osteoblast differentiation | regulation of signaling receptor activity | receptor regulator activity | development of primary male sexual characteristics | negative regulation of epithelial cell proliferation | regulation of mesoderm development | regionalization | cardiac ventricle development | positive regulation of protein modification process | regulation of growth | tissue morphogenesis | digestive system development | sclerotome development | branching morphogenesis of an epithelial tube | regulation of kinase activity | male sex differentiation | regulation of animal organ morphogenesis | regulation of establishment of planar polarity involved in neural tube closure | negative regulation of JUN kinase activity | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | post-anal tail morphogenesis | anatomical structure development | developmental growth involved in morphogenesis | cell surface receptor signaling pathway | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | negative regulation of programmed cell death | male gonad development | negative regulation of muscle cell apoptotic process | positive regulation of cell death | morphogenesis of embryonic epithelium | receptor ligand activity | regulation of response to DNA damage stimulus | regulation of non-canonical Wnt signaling pathway | connective tissue development | negative regulation of intrinsic apoptotic signaling pathway | regulation of intrinsic apoptotic signaling pathway in response to DNA damage | cell death | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | negative regulation of cellular protein metabolic process | negative regulation of cellular component movement | positive regulation of programmed cell death | cellular response to ionizing radiation | regulation of Wnt signaling pathway | regulation of phosphate metabolic process | regulation of JNK cascade | Wnt signaling pathway involved in somitogenesis | morphogenesis of a branching epithelium | positive regulation of canonical Wnt signaling pathway | regulation of peptidyl-serine phosphorylation | anatomical structure formation involved in morphogenesis | negative regulation of protein metabolic process | regulation of stress-activated MAPK cascade | regulation of cell communication | Wnt-activated receptor activity | negative regulation of molecular function | negative regulation of signal transduction | regulation of extrinsic apoptotic signaling pathway via death domain receptors | signaling | somite development | positive regulation of growth | regulation of transcription, DNA-templated | cell development | embryonic digit morphogenesis | negative regulation of peptidyl-tyrosine phosphorylation | regulation of developmental growth | collagen fibril organization | regulation of epithelial cell proliferation | positive regulation of phosphorylation | enzyme regulator activity | morphogenesis of a branching structure | anatomical structure morphogenesis | regulation of endopeptidase activity | positive regulation of fat cell differentiation | reproductive structure development | regulation of nervous system development | regulation of developmental process | regulation of Wnt signaling pathway, planar cell polarity pathway | segmentation | developmental process | negative regulation of canonical Wnt signaling pathway | regulation of cell growth | tube development | regulation of gastrulation | positive regulation of transcription, DNA-templated | negative regulation of cell proliferation | positive regulation of nucleic acid-templated transcription | tube closure | positive regulation of transcription by RNA polymerase II | regulation of epithelial to mesenchymal transition | cardiac chamber development | negative regulation of hydrolase activity | somitogenesis | tube formation | regulation of cell fate commitment | positive regulation of metabolic process | negative regulation of Wnt signaling pathway | regulation of cell projection organization | skeletal system development | immune system process | positive regulation of Wnt signaling pathway | hematopoietic or lymphoid organ development | regulation of stem cell division | regulation of cell death | sex differentiation | negative regulation of cell death | circulatory system development | regulation of midbrain dopaminergic neuron differentiation | negative regulation of locomotion | positive regulation of angiogenesis | endopeptidase activator activity | negative regulation of cell differentiation | regulation of cellular component organization | response to ionizing radiation | positive regulation of signaling | cardiac left ventricle morphogenesis | signal transduction | regulation of signaling | negative regulation of endopeptidase activity | positive regulation of gene expression | planar cell polarity pathway involved in neural tube closure | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

extracellular matrix | cell | collagen-containing extracellular matrix | plasma membrane | extracellular region | extracellular space | cell periphery | membrane

PATHWAYS

NABA_SECRETED_FACTORS | NABA_MATRISOME | NABA_MATRISOME_ASSOCIATED

PROTEIN FAMILY

Netrin domain | Tissue inhibitor of metalloproteinases-like, OB-fold | Frizzled/secreted frizzled-related protein | Netrin module, non-TIMP type | Frizzled domain | Secreted frizzled-related protein 2 | Frizzled cysteine-rich domain superfamily